AI Article Synopsis
- The study utilizes gene array and proteomic analysis to uncover how endostatin inhibits the formation of new blood vessels (antiangiogenesis).
- It clarifies previous uncertainties about endostatin's biological functions and mechanisms.
- The findings aim to further explore the specific molecular pathways that contribute to endostatin's ability to target tumors effectively.
Article Abstract
Up until now, the precise mechanism for endostatin's antiangiogenesis action was not known. In a recent report, have taken advantage of gene array and proteomic analysis to map the antiangiogenic pathways turned on by endostatin. This study resolves some of the controversies surrounding endostatin's biology, and provides a new direction to help dissect the molecular pathways involved in endostatin's selective tumor antiangiogenic effects.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s1535-6108(04)00057-1 | DOI Listing |
Publication Analysis
Top Keywords
endostatin's
4
endostatin's endpoints-deciphering
4
endpoints-deciphering endostatin
4
endostatin antiangiogenic
4
antiangiogenic pathway
4
pathway precise
4
precise mechanism
4
mechanism endostatin's
4
endostatin's antiangiogenesis
4
antiangiogenesis action
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!