Anterior segment optical coherence tomography is a new method to explore the anterior chamber. The target can be focused and defocused with positive or negative lenses to reproduce the conditions of natural accommodation. We studied accommodation in an albino patient because the absence of pigment allows the infrared beam to penetrate the iris and explore the modifications of the ciliary body and the crystalline lens during natural accommodation in a human subject.
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http://dx.doi.org/10.1016/j.jcrs.2003.12.043 | DOI Listing |
Sensors (Basel)
January 2025
Computer-Aided Design and Test (CADT) Research Group, McMaster University, Hamilton, ON L8S 4L8, Canada.
A parallelized field-programmable gate array (FPGA) architecture is proposed to realize an ultra-fast, compact, and low-cost dual-channel ultra-wideband (UWB) pulsed-radar system. This approach resolves the main shortcoming of current FPGA-based radars, namely their low processing throughput, which leads to a significant loss of data provided by the radar receiver. The architecture is integrated with an in-house UWB pulsed radar operating at a sampling rate of 20 gigasamples per second (GSa/s).
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December 2024
College of Civil Engineering, Xiangtan University, Xiangtan 411105, China.
Bridge expansion joints are critical components that accommodate the movement of a bridge caused by temperature fluctuations, concrete shrinkage, and vehicular loads. Analyzing the spatiotemporal deformation of these expansion joints is essential for monitoring bridge safety. This study investigates the deformation characteristics of Hongtang Bridge in Fuzhou, China, using synthetic aperture radar interferometry (InSAR).
View Article and Find Full Text PDFMolecules
December 2024
School of Pharmacy, Kitasato University, Minato-ku, Tokyo 108-8641, Japan.
It is established that reverse hydroxamate analogs of fosmidomycin inhibit the growth of by inhibiting 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), the second enzyme of the non-mevalonate pathway, which is absent in humans. Recent biochemical studies have demonstrated that novel reverse fosmidomycin analogs with phenylalkyl substituents at the hydroxamate nitrogen exhibit inhibitory activities against DXR at the nanomolar level. Moreover, crystallographic analyses have revealed that the phenyl moiety of the -phenylpropyl substituent is accommodated in a previously unidentified subpocket within the active site of DXR.
View Article and Find Full Text PDFBehav Anal Pract
December 2024
Action Behavior Centers, Austin, TX USA.
Play is critical to child development. In early childhood, object play evolves from exploratory behavior to complex symbolic play. Engagement during play, particularly joint engagement, is essential for learning and social interaction.
View Article and Find Full Text PDFCell Biosci
January 2025
State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200438, People's Republic of China.
Background: Neuropathic pain resulting from spinal cord injury (SCI) is associated with persistent hyperactivity of primary nociceptors. Anandamide (AEA) has been reported to modulate neuronal excitability and synaptic transmission through activation of cannabinoid type-1 receptors (CB1Rs) and transient receptor potential vanilloid 1 (TRPV1). However, the role of AEA and these receptors in the hyperactivity of nociceptors after SCI remains unclear.
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