Purpose: To quantify the cyclorotation occurring between wavefront measurement and laser refractive surgery.
Setting: LaserVue Eye Center Ophthalmic Clinic, Santa Rosa, California, USA.
Methods: The pupil camera of the Visx WaveScan wavefront device was used to obtain images of 51 eyes (26 patients) from 5 to 20 minutes before refractive laser surgery. Additionally, an infrared camera was mounted on the Visx Star S3 ActiveTrak excimer laser system to obtain another image immediately before the laser was fired. After surgery, the 2 sets of images were compared to determine the amount of cyclotorsion between the measurement and surgery.
Results: Cyclorotation of individual eyes was as high as 9.5 degrees. The mean was approximately 2.0 degrees for each eye. Binocular excyclotorsion was the predominant trend, affecting 19 of 24 patients.
Conclusions: A low to moderate amount of cyclotorsion was observed in the transition from seated to supine position. Comparison of eye position at the time of measurement to eye position at the time of surgery can be used to adjust the laser ablation algorithm to compensate for this rotational displacement.
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http://dx.doi.org/10.1016/j.jcrs.2003.08.022 | DOI Listing |
The ability to generate high-intensity ultrashort laser pulses is a key driver for advancing the strong-field physics and its applications. Post-compression methods aim to increase the peak intensity of amplified laser pulses via spectral broadening through self-phase modulation (SPM), followed by temporal pulse compression. However, other unavoidable nonlinear self-action effects, which typically occur parallel to SPM, can lead to phase distortions and beam quality degradation.
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Institut für Neuro-und Sinnesphysiologie, Universitätsmedizin Göttingen, Göttingen, Germany.
Spreading depolarization (SD) causes a massive neuronal/glial depolarization, disturbs ionic homeostasis and deranges neuronal network function. The metabolic burden imposed by SD may also generate marked amounts of reactive oxygen species (ROS). Yet, proper optical tools are required to study this aspect with spatiotemporal detail.
View Article and Find Full Text PDFBiomedicines
August 2024
Laboratory of Cellular and Molecular Pathology of Cardiovascular System, Petrovsky National Research Centre of Surgery, 119991 Moscow, Russia.
Myocardial edema is a common symptom of pathological processes in the heart, causing aggravation of cardiovascular diseases and leading to irreversible myocardial remodeling. Patient-based studies show that myocardial edema is associated with arrhythmias. Currently, there are no studies that have examined how edema may influence changes in calcium dynamics in the functional syncytium.
View Article and Find Full Text PDFAppl Spectrosc
October 2024
Applied Sciences Laboratory, Institute for Shock Physics, Washington State University, Spokane, Washington, USA.
We characterize the subsurface thermal degradation of an inert analog of high-explosive molecular crystals (Eu:Y(acac)(DPEPO)) (EYAD) embedded inside of a plastic bonded explosive simulant using feedback-assisted wavefront shaping-based fluorescence and Raman spectroscopies. This technique utilizes wavefront shaping to focus pump light inside a heterogeneous material onto a target particle, which significantly improves its spectroscopic signature. We find that embedding the EYAD crystals in the heterogeneous polymer results in improved thermal stability, relative to bare crystal measurements, with the crystal remaining fluorescent to >612 K inside of the heterogeneous material, while the bare crystal's fluorescence is fully quenched by 500 K.
View Article and Find Full Text PDFInt J Mol Sci
July 2024
Britton Chance Center for Biomedical Photonics and MoE Key Laboratory for Biomedical Photonics, Advanced Biomedical Imaging Facility, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China.
Transient ischemic attack (TIA) is an early warning sign of stroke and death, necessitating suitable animal models due to the associated clinical diagnostic challenges. In this study, we developed a TIA model using flexible spatially targeted photothrombosis combined with real-time blood flow imaging feedback. By modulating the excitation light using wavefront technology, we precisely created a square light spot (50 × 250 µm), targeted at the distal middle cerebral artery (dMCA).
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