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Non-Newtonian blood flow in human right coronary arteries: steady state simulations. | LitMetric

AI Article Synopsis

  • - This study examines blood flow in four different right coronary arteries using bi-plane angiograms and compares both Newtonian and non-Newtonian blood viscosity models to analyze wall shear stress during the cardiac cycle.
  • - Findings indicate that while wall shear stress patterns remain consistent across models in steady flow, the stress magnitude varies depending on the model, especially at different shear rates.
  • - The research recommends using the Generalised Power Law model over the traditional Newtonian model for better accuracy in estimating wall shear stress, particularly at low shear rates, despite the Newtonian model being adequate in mid to high shear regions.

Article Abstract

This study looks at blood flow through four different right coronary arteries, which have been reconstructed from bi-plane angiograms. Five non-Newtonian blood models, as well as the usual Newtonian model of blood viscosity, are used to study the wall shear stress in each of these arteries at a particular point in the cardiac cycle. It was found that in the case of steady flow in a given artery, the pattern of wall shear stress is consistent across all models. The magnitude of wall shear stress, however, is influenced by the model used and correlates with graphs of shear stress versus strain for each model. For mid-range velocities of around 0.2 m s(-1) the models are virtually indistinguishable. Local and global non-Newtonian importance factors are introduced, in an attempt to quantify the types of flows where non-Newtonian behaviour is significant. It is concluded that, while the Newtonian model of blood viscosity is a good approximation in regions of mid-range to high shear, it is advisable to use the Generalised Power Law model (which tends to the Newtonian model in those shear ranges in any case) in order to achieve better approximation of wall shear stress at low shear.

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Source
http://dx.doi.org/10.1016/j.jbiomech.2003.09.016DOI Listing

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