Enantioselective iridium-catalysed intramolecular allylic aminations, using phosphinooxazolines or phosphorus amidites as ligands, provided ee values of >90%, at a catalyst loading of <0.5 mol-%, and displayed a marked preference for intra- over corresponding intermolecular reactions.
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Iridium/chiral phosphoramidite-olefin complex-catalysed enantioselective [3+2] annulation of -ketoarylboron compounds with conjugated dienes.
Chem Commun (Camb)
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Department of Chemistry, Graduate School of Science, Osaka Metropolitan University, Sumiyoshi, Osaka 558-8585, Japan.
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Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
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Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
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Life Sciences Institute and Departments of Medicinal Chemistry, Chemistry, and Microbiology & Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
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