AI Article Synopsis

  • The study explores the reactions of a specific compound, 1,2-dihydro-2-thioxo-4,6(1H,5H)pyrimidinedione, with certain pi-deficient molecules, leading to new and unexpected heterocyclic compounds.
  • The newly formed products include various derivatives like anilinomethylenethioxopyrimidinedione and benzofuropyrimidine, indicating a wide range of chemical transformations.
  • The paper also discusses a potential mechanism for how these products are formed and assesses their biological activity, hinting at possible applications in medicinal chemistry.

Article Abstract

The reactions of 1, 2-dihydro-2-thioxo-4, 6(1H, 5H)pyrimidinedione (1) with some pi-deficients have led to the formation of unexpected heterocyclic products such as anilinomethylenethioxopyrimidinedione, 2, 2'-bis(pyrimidinecarbothioamide), allylthioxopyrimidinecarbothioamide, indenopyranopyrimidine and benzofuropyrimidine derivatives. A possible mechanism for the formation of these products is discussed, and the biological activity is determined.

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Source
http://dx.doi.org/10.1002/ardp.200300802DOI Listing

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