Auditory extinction: the effect of stimulus similarity and task requirements.

Neuropsychologia

Department of Communication Sciences & Disorders, University of Georgia, Athens, GA 30602, USA.

Published: May 2004

Auditory extinction was examined in six patients with right hemisphere lesions, using an auditory double simultaneous stimulation task using letters spoken in male and female voices. Patients had to detect where the stimuli were located, and identify either the letter or the voice (the task-relevant dimension). Auditory extinction was greatest when the two stimuli were the same on the task-relevant dimension, paralleling previous studies of visual extinction. Furthermore, we found that errors of omission were much less frequent in the contralesional field if the patients were not required to report both identity and the location of stimuli. These results are consistent with the notion that auditory extinction may be due in part to a failure to bind together identity and location.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuropsychologia.2003.06.001DOI Listing

Publication Analysis

Top Keywords

auditory extinction
16
task-relevant dimension
8
identity location
8
auditory
5
extinction stimulus
4
stimulus similarity
4
similarity task
4
task requirements
4
requirements auditory
4
extinction
4

Similar Publications

Vagus nerve stimulation rescues impaired fear extinction and social interaction in a rat model of autism spectrum disorder.

J Affect Disord

January 2025

Department of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX 75080, USA; Texas Biomedical Device Center (TxBDC), The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX 75080, USA. Electronic address:

Clinical diagnosis of anxiety disorders is highly prevalent in autism spectrum disorders (ASD). Available treatments for anxiety offer limited efficacy in the ASD population. Vagus nerve stimulation (VNS) has an anxiolytic effect in rats and, when coupled with fear extinction training, VNS enhances extinction of fear in healthy rats.

View Article and Find Full Text PDF

"Ontogenetic Scaling of the Primate Middle Ear".

Am J Primatol

January 2025

Anthropology Department, University of Florida, Gainesville, Florida, USA.

The study of primate auditory morphology is a significant area of interest for comparative anatomists, given the phylogenetic relationships that link primate hearing and the morphology of these auditory structures. Extensive literature addresses the form-to-function relationship of the auditory system (outer, middle, and inner ear) in primates and, by extension, provides insight into the auditory system of extinct primates and even modern humans. We add to this literature by describing the ontogenetic trajectory of the middle ear cavity and ossicular chain (malleus, incus, and stapes) due to their critical role in relaying auditory stimuli for interpretation.

View Article and Find Full Text PDF

Vagus nerve stimulation (VNS) is a therapeutic intervention previously shown to enhance fear extinction in rats. VNS is approved for use in humans for the treatment of epilepsy, depression, and stroke, and it is currently under investigation as an adjuvant to exposure therapy in the treatment of PTSD. However, the mechanisms by which VNS enhances extinction of conditioned fear remain unresolved.

View Article and Find Full Text PDF

Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction.

Mol Brain

November 2024

Laboratory for Sleeping-Brain Dynamics, Research Center for Idling Brain Science, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

Article Synopsis
  • Auditory fear conditioning strategies differ based on working memory, but how they are affected by sleep and extinction in long-term processing remains unclear.
  • In a study on male and female mice, sleep deprivation after conditioning didn't impact delay fear memory during extinction training but did reduce persistent fear in females during remote recall.
  • The findings point to sleep deprivation enhancing extinction in both short and long-term scenarios for different conditioning methods, emphasizing the need to consider emotional memory, sleep, and gender differences in PTSD research and treatment.
View Article and Find Full Text PDF

Methylone regulates fear memory and amygdala activity: A potential treatment for posttraumatic stress disorder?

Prog Neuropsychopharmacol Biol Psychiatry

November 2024

Department of Medicine, MacKay Medical College, New Taipei, Taiwan; Department of Psychiatry, MacKay Memorial Hospital, Taipei, Taiwan. Electronic address:

Methylone (3,4-methylenedioxy-N-methylcathinone) is a rapid-acting entactogen that has demonstrated significant benefits for patients with post-traumatic stress disorder (PTSD) and exhibits good tolerability in phase 1 clinical trials. Despite these promising results, its preclinical effects on fear memory regulation and the underlying mechanisms remain largely unexplored. This study aims to investigate the impact of methylone on auditory fear extinction and its influence on neuronal and synaptic activity in the basolateral amygdala (BLA).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!