Background: The use of review databases for dermatology has been questioned because of the impression that these reviews frequently report finding insufficient evidence to guide therapeutic recommendations.
Objective: We sought to determine the number of review database entries most relevant to dermatology (addressing diseases with skin manifestations whereby a dermatologist may be the primary caregiver) and the percentage of these entries that report sufficient evidence to guide clinical decision making.
Methods: We conducted computerized searches and analysis of reviews in the Cochrane Database of Systematic Reviews and the Database of Abstracts of Reviews of Effectiveness. Database entries were categorized using the face value reports of the original reviewers as: (1) finding sufficient evidence to inform clinical decisions; (2) finding insufficient evidence; or (3) unable to classify with regard to degree of evidence found.
Results: Of all review database entries, 3% (54/1235 in Cochrane Database of Systematic Reviews and 65/2208 in the Database of Abstracts of Reviews of Effectiveness) were deemed relevant to dermatology. In all, 14 entries from the Database of Abstracts of Reviews of Effectiveness were in the process of being written and not available for further evaluation. Of the remaining entries, 40% (42/105) reported finding sufficient evidence. Of the 10 most common dermatologic diagnoses, 8 were addressed in 30% (31/105) of these reviews. Of entries addressing common dermatologic diagnoses, 32% (10/31) reported finding sufficient evidence.
Conclusions: Although few (3%) entries in review databases currently address dermatology topics, entries address many (8/10) of the top 10 dermatology diagnoses. Contrary to popular belief, a substantial number (40%) of such reviews report sufficient evidence to inform clinical decisions making.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0190-9622(03)00883-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
CircDNA2-Educated YTHDF2 Phase Separation Promotes PM-Induced Malignant Transformation Through the Blunting of GADD45A Expression.
Adv Sci (Weinh)
January 2025
School of Public Health, Capital Medical University, Beijing, 100069, P. R. China.
Substantial epidemiological evidence suggests a significant correlation between particulate matter 2.5 (PM) and lung cancer. However, the mechanism underlying this association needs to be further elucidated.
View Article and Find Full Text PDFThe actin cytoskeleton regulates danger-associated molecular pattern signaling and PEP1 RECEPTOR1 internalization.
Plant Physiol
January 2025
State Key Laboratory of Tree Genetics and Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
In plants, cytoskeletal proteins assemble into dynamic polymers that play numerous roles in diverse fundamental cellular processes, including endocytosis, vesicle trafficking, and the spatial distribution of organelles and protein complexes. Plant elicitor peptides (Peps) are damage/danger-associated molecular patterns (DAMPs) that are perceived by the receptor-like kinases PEP RECEPTOR 1 (PEPR1) and PEPR2 to enhance innate immunity and inhibit root growth in Arabidopsis (Arabidopsis thaliana). To date, however, there is little evidence that the actin cytoskeleton of the host cell participates in DAMP-induced innate immunity.
View Article and Find Full Text PDFDeveloping teachers' competency for inclusive education in Ethiopia.
Afr J Disabil
December 2024
Centre of Excellence in Disabilities, Faculty of Education, University of South Africa, Pretoria, South Africa.
Background: In light of the increasing diversity within school populations globally, a pressing need arises for nations to prioritise the enhancement of teachers' competencies in implementing inclusive education, recognising the central role teacher education programmes play in addressing this imperative. Teacher education programmes centred on inclusion not only respond to this global priority but also wield influence on teachers' attitudes, self-efficacy and stress levels when engaging with diverse learners.
Objectives: The study presents an analysis of the effectiveness of a teacher education programme in Ethiopia in developing teachers' competencies for inclusion.
A Study of Orthopedic Patient Leaflets and Readability of AI-Generated Text in Foot and Ankle Surgery (SOLE-AI).
Cureus
December 2024
Trauma and Orthopedics, Lister Hospital, Stevenage, GBR.
Introduction The internet age has broadened the horizons of modern medicine, and the ever-increasing scope of artificial intelligence (AI) has made information about healthcare, common pathologies, and available treatment options much more accessible to the wider population. Patient autonomy relies on clear, accurate, and user-friendly information to give informed consent to an intervention. Our paper aims to outline the quality, readability, and accuracy of readily available information produced by AI relating to common foot and ankle procedures.
View Article and Find Full Text PDFFrom subsidies to stressors: Positively skewed ecological gradients alter biological responses to nutrients in streams.
Ecol Appl
January 2025
U.S. Geological Survey, Lower Mississippi-Gulf Water Science Center, Jackson, Mississippi, USA.
Subsidy-stress gradients offer a useful framework for understanding ecological responses to perturbation and may help inform ecological metrics in highly modified systems. Historic, region-wide shifts from bottomland hardwood forest to row crop agriculture can cause positively skewed impact gradients in alluvial plain ecoregions, resulting in tolerant organisms that typically exhibit a subsidy response (increased abundance in response to environmental stressors) shifting to a stress response (declining abundance at higher concentrations). As a result, observed biological tolerance in modified ecosystems may differ from less modified regions, creating significant challenges for detecting biological responses to restoration efforts.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!