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P R Health Sci J
September 2023
Department of Dermatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Objective: Hansen's disease (HD) is a chronic granulomatous infection endemic in the tropics. Its main clinical manifestations involve the cutaneous, nervous, and musculoskeletal systems. Leprosy reactions (LR) are systemic inflammatory and immune-mediated complications of HD.
View Article and Find Full Text PDFIDCases
June 2023
Department of Dermatology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Erythema nodosum leprosum (ENL), characterized by erythematous subcutaneous nodules with multiorgan involvement and systemic manifestations such as neuritis, arthritis, and orchitis, affects approximately 50 % of patients with lepromatous leprosy (LL). It has also been associated with testicular atrophy and adult-onset hypogonadism, but testicular nodules have rarely been reported. We present the case of a 35-year-old male patient with biopsy confirmed LL who completed multidrug therapy and presented for follow-up with a complaint of testicular tenderness.
View Article and Find Full Text PDFPLoS One
November 2022
Department of Epidemiological Surveillance, Hospital Samic of Puerto Iguazú, Puerto Iguazú, Misiones, Argentina.
Objective: The aim was to analyze the spatial association and relative risk (RR) of leprosy cases diagnosed in southern Brazil and in the Argentinean province of Misiones during 2010 to 2016.
Methods: This ecological-type epidemiological study analyzed data from the Health Ministries of both countries. The analysis included frequency measures, spatial autocorrelation, RR cluster analysis and map construction.
IDCases
May 2019
Department of Internal Medicine, Division of Infectious Diseases and International Medicine, University of South Florida, Tampa, FL, United States.
Approximately 200 cases of leprosy are reported each year in the United States, and about 175 of the cases are diagnosed for the first time. Florida contributes a large number of reported cases each year and is showing an increasing incidence. Studies from other southern U.
View Article and Find Full Text PDFInt J Dermatol
April 2017
Department of Dermatology, University of Puerto Rico, San Juan, Puerto Rico.
Background: Leprosy, or Hansen's disease, is a chronic infectious disease caused by the bacillus Mycobacterium leprae. In 2000, the World Health Organization (WHO) defined the elimination of the disease as a global prevalence of less than one case per 10,000 population. However, disease transmission is an ongoing worldwide public health concern, as evidenced by the more than 220,000 new cases diagnosed each year.
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