Salt sensitivity threshold was measured in 230 patients with arterial hypertension and clinical and functional characteristics of hypertension in patients consuming excessive amounts of salt were studied. Patients with high salt sensitivity threshold consumed more salt with food and represented a special group of patients. These patients suffered especially severe disease which developed earlier than in patients with low threshold. Patients with high salt sensitivity threshold more often had cardiovascular complaints, neurotic traits in psychological status, aggravated heredity. These patients had higher cholesterol level and more often smoked. Clinical course of the disease in patients with high salt sensitivity threshold was more often complicated by hypertensive crises. They also had higher blood pressure throughout 24 hours and impaired circadian blood pressure rhythm. Increased myocardial volume load in patients with high salt sensitivity threshold promoted rapid development of left ventricular hypertrophy and systolic dysfunction.
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