Drug targets: turning the channel (on) for sedation.

Curr Biol

NIH, NIMH, Bldg 36, Rm 1B08, MSC 4034, 9000 Rockville Pike Bethesda, Maryland 20892, USA.

Published: March 2004

Genetic techniques have recently implicated two different ion channels as critical molecular targets for the sedative action of ethanol and intravenous anesthetics. In each case, the target is hyperactivated by the drug.

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http://dx.doi.org/10.1016/j.cub.2004.02.016DOI Listing

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