This study examined the influence of deterministic and stochastic processes (including white Gaussian noise) on reductions in the amount of force output variability through childhood. The structure of the force signal produced during a constant isometric pinch grip task was examined as a function of age (6, 8, and 10 years, and young adults), availability of feedback information (with and without vision), digit (thumb and index finger), and force level (5, 15, 25, and 35% of maximal voluntary contraction). The amount of white Gaussian noise in the force signals was negligible and not age related. The availability of vision led increasingly over the older age groups to lower long-range correlations with more than a single scaling range in a 1/f-like decay process. The reductions in the amount of force variability from childhood to adulthood were related in large part to deterministic organization that increased the adaptive use of higher frequency components, due to the more flexible use of information feedback and feedforward processes.
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http://dx.doi.org/10.1002/dev.10140 | DOI Listing |
Chaos
January 2025
State Key Laboratory of Mechanics and Control for Aerospace Structures, College of Aerospace Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.
The aircraft can experience complex environments during the flight. For the random actions, the traditional Gaussian white noise assumption may not be sufficient to depict the realistic stochastic loads on the wing structures. Considering fluctuations with extreme conditions, Lévy noise is a better candidate describing the stochastic dynamical behaviors on the airfoil models.
View Article and Find Full Text PDFElucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR) specific to that antigen, and the T cell phenotype that emerges following antigen stimulation, remains a mostly unsolved problem, largely due to the lack of large data sets that can be mined to resolve such relationships. Here, we describe Antigen-TCR Pairing and Multiomic Analysis of T-cells (APMAT), an integrated experimental-computational framework designed for the high-throughput capture and analysis of CD8 T cells, with paired antigen, TCR sequence, and single-cell transcriptome. Starting with 951 putative antigens representing a comprehensive survey of the SARS-CoV-2 viral proteome, we utilize APMAT for the capture and single cell analysis of CD8 T cells from 62 HLA A*02:01 COVID-19 participants.
View Article and Find Full Text PDFComput Biol Med
January 2025
Department of Mathematics and Computer Science, Faculty of Science, Port Said University, Street 15, Port Said, 42521, Egypt. Electronic address:
Studying and analysing the various phases and key proteins of cell cycles is essential for the understanding of cell development and differentiation. To this end, mechanistic models play an important role towards a system level understanding of the interactions between cell cycle components. Many quantitative models of cell cycles have been previously constructed using either stochastic or deterministic approaches.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Key Laboratory of Environmental Biotechnology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address:
Biodegradable mulch films (BDMs) are becoming increasingly popular in agriculture and are emerging as an alternative to conventional polyethylene (PE) films. However, the intricate details surrounding the establishment and growth of microorganisms on BDMs and PE during their degradation in agricultural fields remain unclear. In this study, the succession of bacterial communities in farmland soil and the plastispheres of PE and BDMs were compared through 16S rRNA gene high-throughput sequencing and real-time PCR.
View Article and Find Full Text PDFMath Biosci
January 2025
Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong, China. Electronic address:
Amphibian decline and extinction have been observed on a global scale, highlighting the urgency of identifying the underlying factors. This issue has long been recognized as a critical concern in conservation ecology and continues to receive significant attention. Pathogen infection, in particular the chytrid fungus Batrachochytrium dendrobatidis, is postulated as a key factor contributing to the decline of certain species within specific regions.
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