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BACKGROUND Primary cutaneous lymphomas (PCL) are a multifaceted spectrum of cutaneous T cell lymphoma (CTCL) and cutaneous B cell lymphomas (CBCL). Mycosis fungoides (MF) is a rare subset of CTCL that primarily affects adults, and its occurrence in children is exceedingly rare. Most pediatric MF manifests as hypopigmented patches resembling other benign dermatoses, causing diagnostic challenges.

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Scleromyxedema is a rare skin mucinosis often associated with systemic involvement and monoclonal gammopathy (MG). No formal recommendation for management with therapeutic plasma exchange (TPE) has been published due to rarity. This paper reports a 42-year-old male with progressive scleromyxedema.

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  • - An 11-year-old girl presented with high fever, headaches, abdominal pain, and a unique skin rash, leading to a challenging diagnosis of Lyme borreliosis.
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Clinical and pathological characteristics of a dog with scleromyxoedema.

J Small Anim Pract

December 2024

Dermatology Referral Service, Clinique Vétérinaire Saint Bernard, Lomme, France.

An 8-year-old male cross-Labrador retriever was presented for a progressive appearance of folds all over the body of the dog. Scleromyxoedema was diagnosed based on clinical signs and histopathological features. Clinical signs were characterised by a papular and vesicular eruption and severe skin thickening causing exuberant folds along with concurrent severe osteoarthritis of the coxofemoral joints.

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  • * The patient experienced skin rashes and elevated glucagon levels throughout treatment but underwent several surgeries, including pancreatic and liver tumor resections, which led to initial improvements in skin symptoms and glucagon levels post-surgery.
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