The increasing size of the transplant waiting list and the increasing use of expanded criteria donors places a premium on efficient use of recovered organs. Maximal organ utilization often necessitates organ sharing between transplant organizations. Optimal organ sharing requires rapid, integrated communication of donor information combined with expedited organ transportation. For more than 20 years, the United Network for Organ Sharing's Organ Center has fulfilled this task for the United States transplant community. This overview details a brief history of United States organ sharing and the role played by the Organ Center. The current scope and modes of Organ Center operations are detailed.
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http://dx.doi.org/10.1097/01.tp.0000113232.90613.d5 | DOI Listing |
Clin Transplant
January 2025
Division of Abdominal Transplant, Department of Surgery, Stanford University Medical Center, Stanford, California, USA.
Background: In July 2023, the OPTN adopted MELD3.0 to address sex-based disparities in liver transplantation (LT) opportunity and waitlist mortality. No studies have proven that MELD3.
View Article and Find Full Text PDFRadiother Oncol
December 2024
Department of Digital Medicine, School of Biomedical Engineering and Medical Imaging, Army Medical University, Chongqing 400038, China. Electronic address:
Background And Purpose: Accurate segmentation of the clinical target volume (CTV) is essential to deliver an effective radiation dose to tumor tissues in cervical cancer radiotherapy. Also, although automated CTV segmentation can reduce oncologists' workload, challenges persist due to the microscopic spread of tumor cells undetectable in CT imaging, low-intensity contrast between organs, and inter-observer variability. This study aims to develop and validate a multi-task feature fusion network (MTF-Net) that uses distance-based information to enhance CTV segmentation accuracy.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; State Key Laboratory for Quality Assurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address:
Ethnopharmacological Relevance: Ischemic stroke (IS) is a major cause of mortality. Inflammation exerts an essential part of brain-heart communication after IS. Naoxintong capsules (NXT), derived from the classical Traditional Chinese Medicine (TCM) formulation Bu-Yang-Huan-Wu-Tang, are extensively employed in China to manage IS, myocardial infarction (MI), and atherosclerosis.
View Article and Find Full Text PDFEur Neuropsychopharmacol
December 2024
Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Academy of Military Medical Sciences, 27 Taiping Road, Beijing 100850, China. Electronic address:
Unipolar depression is typically regarded as a psychiatric disorder, yet it frequently coexists with various major diseases. This study employs a Disease-Wide Association Study (DWAS) approach to map the disease continuum surrounding unipolar depression, analyzing data from a registry cohort of 392,423 individuals, including 43,280 diagnosed cases of unipolar depression. Significant associations were identified between depression and comorbidities across multiple organ systems, including both mental and physical disorders.
View Article and Find Full Text PDFJ Plant Res
December 2024
Instituto de Pesquisas Jardim Botânico Do Rio de Janeiro (JBRJ), Diretoria de Pesquisa Científica, Rio de Janeiro, RJ, 22460-030, Brazil.
Erythrina is a Pantropical bird-pollinated genus of Fabaceae. Thus, its flowers are usually large, showy, red or yellowish, offering nectar as the principal resource. There are two main interaction systems with birds in Erythrina: in one, the inflorescences are erect and the flowers are horizontal, offering no landing platform; in the other, the inflorescences are horizontal and the flower parts are more exposed.
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