The paper contains the results of examinations of hemodynamics of the eye and brain in patients with primary open-angle glaucoma (POAG) obtained by the authors also by means of rheoophthalmography made to determine the functional status of intraocular vessels. New methods are suggested for diagnostic interpretation, which enhance the importance of rheography in examinations of hemodynamics of the eye and brain in patients with glaucoma. The authors used self-learning artificial neuron networks to process Fourie- and wavelet factors, obtained in novel rheoophthalmograms processing, which made it possible to recommend the described method for an early diagnosis of POAG.
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Neurology
February 2025
Division of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
Pathogenic variants in cause congenital muscular dystrophy through hypoglycosylation of alpha-dystroglycan (OMIM #615350). The established phenotypic spectrum of GMPPB-related disorders includes recurrent rhabdomyolysis, limb-girdle muscular dystrophy, neuromuscular transmission abnormalities, and congenital muscular dystrophy with variable brain and eye anomalies. We report a 9-month-old male infant with congenital muscular dystrophy, infantile spasms, and compound heterozygous pathogenic variants (c.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Purpose: To investigate the relationship between nocturnal blood pressure (BP) dip and parapapillary choroidal vessel density (pCVD) in patients with normal-tension glaucoma (NTG).
Methods: This study analyzed 267 eyes of 267 untreated NTG patients who underwent 24-hour (h) intraocular pressure (IOP) and ambulatory BP monitoring in the habitual position. Patients were classified into 3 groups [non-dippers (nocturnal BP dip < 10%), dippers (nocturnal BP dip between 10% and 20%, and over-dippers (nocturnal BP dip > 20%)], and pCVDs were measured by using optical coherence tomography angiography (OCTA) images.
Br J Anaesth
January 2025
Perioperative Outcomes and Informatics Collaborative, Winston-Salem, NC, USA; Outcomes Research Consortium, Houston, TX, USA; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Most postoperative deaths occur on general wards, often linked to complications associated with untreated changes in vital signs. Monitoring in these units is typically intermittent checks each shift or maximally every 4-6 h, which misses prolonged periods of subtle changes in physiology that can herald a critical downstream event. Continuous monitoring of vital signs is therefore intuitively necessary for patient safety.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Department of Research, Universidad Francisco Marroquín, 13 av, Guatemala City 01011, Guatemala.
A 17-year-old female presented with a mass in the right nasal fossa and eye protrusion. Imaging revealed a large osseous mass originating from the right turbinates, causing exophthalmos without tissue invasion. A partial resection via the Caldwell-Luc approach was performed, but hemodynamic instability halted the procedure, leaving a residual mass.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Cardiovascular Hospital, Renmin Hospital of Wuhan University, Wuhan, China.
Background: Oral microenvironmental disorders are associated with an increased risk of heart failure with preserved ejection fraction (HFpEF). Hyperspectral imaging (HSI) technology enables the detection of substances that are visually indistinguishable to the human eye, providing a noninvasive approach with extensive applications in medical diagnostics.
Objective: The objective of this study is to develop and validate a digital, noninvasive oral diagnostic model for patients with HFpEF using HSI combined with various machine learning algorithms.
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