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History and historical DNA: Identity of Chelodina intergularis Fry, 1915 and type localities of C. intergularis and C. rugosa Ogilby, 1890.
Zootaxa
May 2024
Museum of Zoology; Senckenberg Dresden; 01109 Dresden; Germany.
Based on the phylogenetic placement of a near-complete mitogenome sequence of the holotype of Chelodina intergularis Fry, 1915 generated with hDNA approaches, we present evidence for the synonymy of this nominal species with Chelodina rugosa Ogilby, 1890. The type specimens of both taxa are housed in the Australian Museum, Sydney. Scrutinizing historical records, we conclude that the type locality of both taxa is most likely the vicinity of Somerset, at the northern extremity of Cape York Peninsula, Queensland, Australia.
View Article and Find Full Text PDFSARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
JAMA Netw Open
May 2024
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: SARS-CoV-2 viral load (VL) in the nasopharynx is difficult to quantify and standardize across settings, but it may inform transmission potential and disease severity.
Objective: To characterize VL at COVID-19 diagnosis among previously uninfected and unvaccinated individuals by evaluating the association of demographic and clinical characteristics, viral variant, and trial with VL, as well as the ability of VL to predict severe disease.
Design, Setting, And Participants: This secondary cross-protocol analysis used individual-level data from placebo recipients from 4 harmonized, phase 3 COVID-19 vaccine efficacy trials sponsored by Moderna, AstraZeneca, Janssen, and Novavax.
Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.
Phys Rev Lett
February 2024
Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551-0808, USA.
Article Synopsis
- * This experiment produced 2.05 MJ of laser energy, resulting in 3.1 MJ of total fusion yield, which exceeds the Lawson criterion for ignition, demonstrating a key milestone in fusion research.
- * The report details the advancements in target design, laser technology, and experimental methods that contributed to this historic achievement, validating over five decades of research in laboratory fusion.
Detailed clinical assessment is critical to allow sensitive evaluation of the eye and its management. As technology advances, these assessment techniques can be adapted and refined to improve the detection of pathological changes of ocular tissue and their impact on visual function. Enhancements in optical medical devices including spectacle, contact, and intraocular lenses have allowed for a better understanding of the mechanism and amelioration of presbyopia and myopia control.
View Article and Find Full Text PDFRisk of COVID-19 after natural infection or vaccination.
EBioMedicine
October 2023
Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Article Synopsis
- Study explores the protective effects of previous SARS-CoV-2 infection and hybrid immunity (infection plus vaccination) against COVID-19, using data from various vaccine trials.
- Participants were grouped based on their previous infection status and whether they received a vaccine, with a main focus on confirmed COVID-19 cases post-treatment.
- Results indicated that individuals with previous infections had a significantly lower risk of contracting COVID-19, and hybrid immunity generally offered better protection than vaccination alone, emphasizing the effectiveness of both natural infection and vaccination in preventing severe disease.
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