A criterion for determining the acceptability of a case presented for the American Board of Orthodontics (ABO) Phase III clinical examination is case difficulty. Case difficulty can often be subjective; however, it is related to case complexity, which can be quantifiable. Over the past 5 years, the ABO has developed and field-tested a discrepancy index, made up of various clinical entities that are measurable and have generally accepted norms. These entities summarize the clinical features of a patient's condition with a quantifiable, objective list of target disorders that represent the common elements of an orthodontic diagnosis: overjet, overbite, anterior open bite, lateral open bite, crowding, occlusion, lingual posterior crossbite, buccal posterior crossbite, ANB angle, IMPA, and SN-GoGn angle. The greater the number of these conditions in a patient, the greater the complexity and the greater the challenge to the orthodontist. The ABO is considering several options for applying the discrepancy index to the Phase III clinical examination.
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http://dx.doi.org/10.1016/j.ajodo.2004.01.005 | DOI Listing |
BMC Bioinformatics
January 2025
Centro de Salud Retiro, Hospital Universitario Gregorio Marañon, C/Lope de Rueda, 43, 28009, Madrid, Spain.
Background: Natural language processing (NLP) enables the extraction of information embedded within unstructured texts, such as clinical case reports and trial eligibility criteria. By identifying relevant medical concepts, NLP facilitates the generation of structured and actionable data, supporting complex tasks like cohort identification and the analysis of clinical records. To accomplish those tasks, we introduce a deep learning-based and lexicon-based named entity recognition (NER) tool for texts in Spanish.
View Article and Find Full Text PDFExp Mol Med
January 2025
Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.
The spatial organization of cells within a tissue is dictated throughout dynamic developmental processes. We sought to understand whether cells geometrically coordinate with one another throughout development to achieve their organization. The pancreas is a complex cellular organ with a particular spatial organization.
View Article and Find Full Text PDFJ Pediatr Urol
December 2024
Department of Urology, Sri Sathya Sai Institute of Higher Medical Sciences, Prashantigram, Puttaparthi, Andhra Pradesh 515134, India.
Introduction: Graft fibrosis following the first stage of a free graft staged hypospadias repair is a difficult scenario where the management has traditionally been to excise the graft and replace it with a new graft. However, still the risk of recurrent fibrosis remains making it difficult to proceed to the second stage and tubularising a fibrosed graft practically ensures a breakdown. Herein, we present our way of using parameatal based flip flap urethroplasty as a salvage procedure in this situation.
View Article and Find Full Text PDFOral Maxillofac Surg Clin North Am
January 2025
Department of Maxillofacial Prosthetics and Prosthodontics, Naval Medical Center San Diego California, USA.
Computer-guided full-arch dental rehabilitation, which is highly technique-sensitive, benefits from advancements in 3-dimensional-printed guides and open-source software. Critical pre-surgical planning includes patient selection, health history evaluations, and detailed imaging like cone beam computed tomography scans. Various surgical guides-freehand, static, dynamic, stackable, and interchangeable-are used based on case complexity, with stackable guides improving workflow efficiency.
View Article and Find Full Text PDFZhonghua Yi Xue Yi Chuan Xue Za Zhi
October 2025
Department of Pediatric Neurology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Objective: To explore the clinical and genetic characteristics of two children diagnosed with two rare genetic diseases simultaneously.
Methods: Two children with comorbidity of two genetic diseases due to dual genetic mutations diagnosed at the Third Affiliated Hospital of Zhengzhou University respectively in May 2022 and March 2023 were selected as the study subjects. Clinical and genetic data of the two children were retrospectively analyzed.
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