Objective: To investigate the visual attention mechanisms of brain, the "cue-target" experimental paradigm was adopted, and the attended range was cued by different Chinese characters.
Method: Sixteen healthy young participants (8 male and 8 female, 19-24 years old with an average of 21) served as the subjects. The stimulus sequence was "background-cue-target". The background was comprised of three homocentric white circles. Cue was the Chinese character " large", "median" and " small ". There were 8 capital English letters in each circle, which formed three homocentric circles. "T" was designed as the target stimulus. When the cue was large, the target "T" appeared within the three circles. When the cue was medium, "T" appeared within the medium and small circles. When the cue was small, the T maybe appeared only within the small circle.
Result: The reaction time became short with the decrease of the cue scale, while P1 and N1 components amplitudes increased.
Conclusion: These results not only provided the electrophysiological evidence for the spot light theory, but also indicated that the spot-light effect happened at the early period of the information processing.
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Multisens Res
November 2024
Department of Cognitive Science, Faculty of Media and Knowledge Sciences, University of Malta, Msida, Malta.
In two experiments, we explored whether cross-modal cues can be used to improve foraging for multiple targets in a novel human foraging paradigm. Foraging arrays consisted of a 6 × 6 grid containing outline circles with a small dot on the circumference. Each dot rotated from a random starting location in steps of 30°, either clockwise or counterclockwise, around the circumference.
View Article and Find Full Text PDFCortex
January 2025
Department of Psychology, University of Groningen, 9712TS Groningen, the Netherlands.
Pupil size is modulated by various cognitive factors such as attention, working memory, mental imagery, and subjective perception. Previous studies examining cognitive effects on pupil size mainly focused on inducing or enhancing a subjective experience of brightness or darkness (for example by asking participants to attend to/memorize a bright or dark stimulus), and then showing that this affects pupil size. Surprisingly, the inverse has never been done; that is, it is still unknown what happens when a subjective experience of brightness or darkness is eliminated or strongly reduced even though bright or dark stimuli are physically present.
View Article and Find Full Text PDFDyslexia
November 2024
School of Allied Health, Exercise and Sports Sciences, Charles Sturt University, Port Macquarie, Australia.
This study aimed to examine the effect of visual pre-cueing presented at different time intervals in the response time of dyslexic and non-dyslexic children. Fifteen dyslexic and 15 non-dyslexic children performed a computerised four-choice reaction time task across four conditions: no pre-cue and a 43-ms time interval (or duration) of a centralised dot appearing in the stimulus circle at 43, 86 or 129 ms prior to the stimulus. Each condition was repeated eight times, totaling 32 trials, and presented in a random order.
View Article and Find Full Text PDFClin Cancer Res
December 2024
Department of Medicine, Fred Hutchinson Cancer Center and University of Washington, Seattle, Washington.
Purpose: This multicenter phase Ib study investigated trastuzumab deruxtecan (T-DXd) plus nivolumab in patients with HER2-expressing metastatic breast cancer (mBC) and metastatic urothelial cancer (mUC).
Patients And Methods: Part 1 determined the recommended dose for expansion of T-DXd plus nivolumab. Part 2 evaluated efficacy and safety; the primary endpoint was confirmed objective response rate by independent central review.
Cogn Res Princ Implic
August 2024
Sirona Medical, San Francisco, USA.
Irrelevant salient distractors can trigger early quitting in visual search, causing observers to miss targets they might otherwise find. Here, we asked whether task-relevant salient cues can produce a similar early quitting effect on the subset of trials where those cues fail to highlight the target. We presented participants with a difficult visual search task and used two cueing conditions.
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