Purpose: To explore the application and the anaesthetic effect of primacaine in anaesthetizing the pulp.

Methods: 162 teeth of pulpitis underwent submucous infiltration anaesthesia via the labial or buccal side (single side anaesthesia). There were 94 teeth of acute pulpitis and 68 teeth of chronic pulpitis among them. Anaesthesia effect were observed.Maxillary, mandibular molars and mandibular premolar were respectively divided into two groups, one underwent submucous infiltration anaesthesia via the labial or buccal and lingual sides (double sides anaesthesia), the other underwent single side anaesthesia. The data was analysed with X(2) test.

Results: The effective rate of single side anaesthesia was 72.8%, There was no significant difference between acute and chronic pulpitis(P>0.05). For mandibular molar,the effect of double side anaesthesia was better than the single side anaesthesia (P<0.05).

Conclusions: Primacaine had a good anaesthesia effect when the teeth of pulpitis underwent pulpectomy. In order to get perfect anaesthetic effect, the double side anaesthesia for the mandibular molar was suggested.

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