Apoptosis as a tool for therapeutic agents in haematological diseases.

Expert Opin Biol Ther

Department of Medical Laboratory Sciences, College of Applied Medical Sciences, King Faisal University, PO Box 1982, Dammam 31451, Kingdom of Saudi Arabia.

Published: March 2004

AI Article Synopsis

  • Apoptosis is a crucial process of programmed cell death that plays a significant role in various biological systems and is linked to many diseases.
  • Understanding apoptosis better is hoped to lead to new treatment options, especially for conditions like leukemia and lymphoma.
  • Recent advancements focus on manipulating apoptosis pathways to improve clinical outcomes in treating haematological diseases.

Article Abstract

Apoptosis, an active mechanism of cell death, is an important process in many biological systems. Apoptosis is thought to contribute to many disease processes. This notion has raised expectations that therapeutic opportunities will naturally follow once a better understanding of these processes has been achieved. The regulation of apoptosis in normal and malignant haematological diseases represents an important therapeutic approach in the treatment of leukaemia and lymphoma. This review summarises recent developments in the clinical manipulation of apoptosis pathways in haematological therapy.

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Source
http://dx.doi.org/10.1517/14712598.4.3.407DOI Listing

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