AI Article Synopsis
- A new compound was created by modifying hypocrellin B, resulting in a diamino-substituted hypocrellin.
- The new compound absorbs red light much better than both the original hypocrellins and their derivatives.
- It also generates more active oxygen species, which will significantly boost its effectiveness in photodynamic therapy.
Article Abstract
A novel diamino-substituted hypocrellin derived from hypocrellin B (HB) was synthesized by a mild method. The red absorption of the resulting product was significantly enhanced relative to the parent hypocrellins and any other hypocrellin derivatives, and the active oxygen species generating abilities were enhanced distinctly, which will remarkably improve its photodynamic therapy effectiveness.
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| http://dx.doi.org/10.1016/j.bmcl.2004.01.003 | DOI Listing |
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