Objective: To develop and evaluate a standardised method for unbiased measurements of epithelial thickness taking the variability of the dermal papillae in consideration.
Methods: A computer-assisted measurement program suitable for haematoxylin and eosin routine stained specimens has been developed.
Results: The developed program was designed to measure four different distance parameters, taking the number, height and width of dermal papillae into account. The measurement program gave very accurate results compared with manual measurements. The measurement results can be presented as tables or star graphs, and the results can be further processed by multivariate analysis.
Conclusion: The computer-assisted measurement program is considered to be a valuable and reliable tool for measurements of epithelial thickness, irrespectively of the variability of the epithelial morphology. Since length, size and number of the papillae may change with certain pathological conditions, age and also under hormonal influence, this method can be a helpful diagnostic tool.
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http://dx.doi.org/10.1016/j.micron.2003.11.016 | DOI Listing |
J Environ Manage
January 2025
CE3C-Centre for Ecology, Evolution and Environmental Changes & CHANGE, Global Change and Sustainability Institute, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, C2, Piso 5, 1749-016, Lisboa, Portugal. Electronic address:
Fires are increasingly affecting tropical biomes, where landscape-fire interactions remain understudied. We investigate the fire-proneness-the likelihood of a land use or land cover (LULC) type burning more or less than expected based on availability-in the Brazilian Atlantic Forest (AF). This biodiversity hotspot is increasingly affected by fires due to human activities and climate change.
View Article and Find Full Text PDFJ Occup Environ Med
November 2024
Department of Health Behavior, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Objective: As the COVID-19 pandemic presented new challenges for businesses and worker safety and health, an interdisciplinary team launched the COVID-19 Worksite Impact Survey to assess COVID-19-related impacts and responses at small and medium businesses in 10 North Carolina counties.
Methods: We collected data from October 2 to December 1, 2020, and analyzed survey results to evaluate businesses' operational changes, concerns, needs, pandemic preparedness, workplace health promotion programming, and infection control practices.
Results: Most businesses, including essential ones, were inadequately prepared for the pandemic and did not implement the most effective COVID-19 infection control practices.
Proc Natl Acad Sci U S A
January 2025
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305.
Exercising regularly promotes health, but these benefits are complicated by acute inflammation induced by exercise. A potential source of inflammation is cell-free DNA (cfDNA), yet the cellular origins, molecular causes, and immune system interactions of exercise-induced cfDNA are unclear. To study these, 10 healthy individuals were randomized to a 12-wk exercise program of either high-intensity tactical training (HITT) or traditional moderate-intensity training (TRAD).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Electronics Sciences and Technology Division, United States Naval Research Laboratory, Washington, DC 20375.
This study presents the direct measurement of proton transport along filamentous , or cable bacteria. Cable bacteria are filamentous multicellular microorganisms that have garnered much interest due to their ability to serve as electrical conduits, transferring electrons over several millimeters. Our results indicate that cable bacteria can also function as protonic conduits because they contain proton wires that transport protons at distances >100 µm.
View Article and Find Full Text PDFJ Speech Lang Hear Res
January 2025
Department of Psychology, University of Lethbridge, Alberta, Canada.
Purpose: This study investigates how Mandarin-English bilingual students in Canada produce Mandarin tones and how this is influenced by factors such as tone complexity, cross-linguistic influences, and speech input.
Method: Participants were 82 students enrolled in a Chinese bilingual program in Western Canada. Students were recruited from Grades 1, 3, and 5 and divided into two groups based on their home language backgrounds: The heritage language group had early and strong input in Mandarin, and the second language (L2) group received mostly English input at home.
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