Objective: The aim of this study was to determine the efficacy and safety of viscosupplementation applied to the hip joint with the lateral approach and ultrasound guidance and to show whether this can be an alternative treatment model in hip osteoarthritis (OA).
Methods: We performed three hylan G-F injections each to 14 patients with hip OA. We evaluated visual analog score (VAS), Lequesne hip OA severity index, 15-meter walking time before injections and 30 and 90 days after injections, and patient satisfaction.
Results: We established that after 30 respectively 90 days of treatment, VAS, Lequesne hip OA severity index, and 15-meter walking time were statistically significantly lower than before the treatment. This decrease continued after the 30th day. No side effects or complications were observed.
Conclusions: Viscosupplementation performed under ultrasound guidance with the lateral approach is an effective and safe method and can be an alternative treatment of hip OA.
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http://dx.doi.org/10.1007/s00296-004-0441-5 | DOI Listing |
Expert Rev Pharmacoecon Outcomes Res
December 2024
Health Economics and Value Assessment Manager COPAC. Sanofi - Colombia, Bogotá.
Background: Viscosupplementation is a viable alternative for managing knee osteoarthritis, showing potential to delay the need for total joint replacement in affected patients.
Methods: We constructed an economic model that compared viscosupplementation with hylan G-F 20, with available hyaluronic acids, and no viscosupplementation over a 5-year period, from the perspective of the Colombian general health system. Time until total knee replacement, sourced from published literature, informed the model.
Drugs Context
April 2024
Zucker School of Medicine at Hofstra/Northwell, Northwell Phelps Hospital, Sleepy Hollow, NY, USA.
Background: Clinical trials on the use of viscosupplementation with hyaluronic acid (HA) in patients with knee osteoarthritis (KOA) are inconsistent, making it challenging to determine its value in clinical practice. One issue is the availability of various HA products on the market; differences in their chemical features can impact patient outcomes. Herein, we assess the efficacy and safety of three once-weekly intra-articular (IA) injections of Hylan G-F 20, a high-molecular-weight and highly crosslinked HA product, in patients with KOA.
View Article and Find Full Text PDFAdv Ther
January 2024
Department of Orthopaedics, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.
Introduction: Hyaluronic acid (HA) use to treat knee osteoarthritis (OA) has been extensively investigated in the literature. There are also multiple economic assessments comparing intra-articular HAs with oral anti-inflammatory medicines and other conservative measures (NSAIDs), as well as different types and formulations of HA. Owing to the broad landscape of evidence across this area, it is important to further understand the empirical data comparing HA products, as well as the health economic implications that exist between commercially available HAs.
View Article and Find Full Text PDFCurr Ther Res Clin Exp
June 2023
Premier Orthopaedics and Sports Medicine, Glen Mills, Massachusetts.
Background: Knee osteoarthritis is a leading cause of disability worldwide. Symptoms can vary over time, leading to episodes of worsened symptoms known as flares. Intra-articular injection of hyaluronic acid has demonstrated long-term symptomatic relief in the broader knee osteoarthritis population, although its use in the flare population has not been extensively examined.
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