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A 64-year-old male with Aspergillus fumigatus infection that had disseminated from the lung to the ankle and adjacent bone was treated successfully with posaconazole after therapy with itraconazole and amphotericin B lipid complex failed. Marked clinical improvement occurred within 6 weeks of initiation of posaconazole therapy; after 6 months, infection had resolved at all sites. The patient has had no recurrence of infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC356879 | PMC |
| http://dx.doi.org/10.1128/JCM.42.3.1376-1378.2004 | DOI Listing |
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