We have identified a potential quality control strain of Mycobacterium tuberculosis to monitor isoniazid susceptibility testing. This strain (strain A) has a stable phenotypic low-level resistance to isoniazid, has a mutation of C (-15) --> T in the inhA promoter region, and gave consistent susceptibility test results in 141 laboratories.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC356860 | PMC |
http://dx.doi.org/10.1128/JCM.42.3.1294-1295.2004 | DOI Listing |
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