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Sensitisation to Lep d 2- Lepidoglyphus destructor allergy in asthma and rhinitis.
Eur Ann Allergy Clin Immunol
October 2024
Department of Immunoallergology, Arrábida Local Unit of Health, Hospital de São Bernardo, Setúbal, Portugal.
Article Synopsis
- Mites, especially Storage Mites (SM), play a significant role in allergic diseases like asthma and rhinitis, affecting about 1.5% of the global population, with a focus on their impact in urban areas, particularly the Mediterranean.
- The study examined patients monosensitised to the major allergen Lep d 2, using advanced allergy testing methods, finding that a notable percentage of these individuals primarily suffer from allergic rhinitis, with some also exhibiting asthma symptoms.
- Results indicate that sensitisation to Lep d 2, while showing lower sIgE levels compared to polysensitised patients, plays an important role in persistent allergic respiratory conditions, underlining the need
Hand eczema in Italian patients referred for patch testing: A retrospective SIDAPA study (2016-2023).
Contact Dermatitis
January 2025
Section of Dermatology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Article Synopsis
- Hand eczema (HE) significantly impacts quality of life and lacks comprehensive data for Italian patients undergoing patch testing, highlighting the need for a better understanding of this condition.
- A study analyzed 1,597 HE patients over seven years, revealing key demographic and clinical information, such as that 60.2% were in the HE-only group and 33.2% of these had occupational dermatitis.
- Results showed common allergic and irritant responses in HE-only patients, with significant patch test reactions primarily to nickel and various preservatives, emphasizing unique traits within this patient population.
High prevalence but no current clinical relevance of methyldibromo glutaronitrile since its ban in Turkey in 2015.
Contact Dermatitis
October 2024
Department of Dermatology and Venereology, İstanbul Faculty of Medicine, İstanbul University, Istanbul, Turkey.
Background: Regulatory actions significantly reduced methyldibromo glutaronitrile (MDBGN)-induced allergic contact dermatitis (ACD) from cosmetics in Europe. Turkey banned MDBGN in 2015.
Objectives: To assess sensitization and ACD rates to MDBGN before and after its ban in Turkey.
Severely compromised supply of patch test allergens in Europe hampers adequate diagnosis of occupational and non-occupational contact allergy. A European Society of Contact Dermatitis (ESCD), European Academy of Allergy and Clinical Immunology (EAACI), European Academy of Dermatology and Venereology (EADV) task forces 'Contact Dermatitis' and 'Occupational Skin Disease' position paper.
Contact Dermatitis
August 2024
National Allergy Research Centre, Department of Skin and Allergy, University of Copenhagen, Gentofte Hospital, Copenhagen, Denmark.
Patch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of Type IV patch test (PT) allergens in Europe, however, is currently scarce. This severely compromises adequate diagnostics of contact allergy, leading to serious consequences for the affected patients.
View Article and Find Full Text PDFThe new Italian SIDAPA Baseline Series for patch testing (2023): an update according to the new regulatory pathway for contact allergens.
Ital J Dermatol Venerol
April 2024
Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Allergic contact dermatitis (ACD) is a common inflammatory skin disease caused by delayed hypersensitivity to chemical and biotic contact allergens. ACD significantly affects the patients' quality of life negatively impacting both occupational and non-occupational settings. Patch testing is the gold standard diagnostic in vivo test to precise the ACD etiology and to correctly perform prevention.
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