Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Testing the kinetic tradeoff between bicarbonate versus phosphoenolpyruvate affinity and glucose-6 phosphate response of phosphoenolpyruvate carboxylase from two C grasses.
Photosynth Res
January 2025
School of Biological Sciences, Washington State University, 406 Abelson Hall, Pullman, WA, 99164, USA.
Phosphoenolpyruvate (PEP) carboxylase (PEPC) has an anaplerotic role in central plant metabolism but also initiates the carbon concentrating mechanism during C photosynthesis. The C PEPC has different binding affinities (K) for PEP (K) and HCO (K), and allosteric regulation by glucose-6-phosphate (G6-P) compared to non-photosynthetic isoforms. These differences are linked to specific changes in amino acids within PEPC.
View Article and Find Full Text PDFDNA Dendron Tagging as a Universal Way to Deliver Proteins to Cells.
J Am Chem Soc
January 2025
Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
The use of proteins as intracellular probes and therapeutic tools is often limited by poor intracellular delivery. One approach to enabling intracellular protein delivery is to transform proteins into spherical nucleic acid (proSNA) nanoconstructs, with surfaces chemically modified with a dense shell of radially oriented DNA that can engage with cell-surface receptors that facilitate endocytosis. However, proteins often have a limited number of available reactive surface residues for DNA conjugation such that the extent of DNA loading and cellular uptake is restricted.
View Article and Find Full Text PDFKey attributes of nitrocellulose-based energetic materials and recent developments.
Heliyon
January 2025
Centre for Tropicalization (CENTROP), Defence Research Institute, Universiti Pertahanan Nasional Malaysia, Kem Sungai Besi, 57000, Kuala Lumpur, Malaysia.
Nitrocellulose (NC)-based propellants have played a pivotal role in the development of energetic materials for both military and civilian applications. This review offers a comprehensive exploration of NC-based propellants, tracing their evolution from their historical origins as smokeless gunpowder to modern advancements. It discusses the chemical composition and classifications of NC propellants, along with continuous efforts to refine smokeless powder formulations through studies on smoke formation, residues, and additives.
View Article and Find Full Text PDFSynthesis and Biological Evaluation of 5'-Deoxy-adenosine Derivatives as A Adenosine Receptor Ligands.
ACS Med Chem Lett
January 2025
Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
The A Adenosine Receptor (AAR) is an important therapeutic target due to its role in inflammation and immune response regulation. Herein, we synthesized and evaluated 5'-deoxy-adenosine derivatives with oxygen at the 4'-position, comparing them to previously studied 4'-thionucleosides. Compound exhibited the highest binding affinity ( = 5.
View Article and Find Full Text PDFDevelopment of a TSR-based method for understanding structural relationships of cofactors and local environments in photosystem I.
BMC Bioinformatics
January 2025
Department of Chemistry, University of Louisiana at Lafayette, Lafayette, LA, 70504, USA.
Background: All chemical forms of energy and oxygen on Earth are generated via photosynthesis where light energy is converted into redox energy by two photosystems (PS I and PS II). There is an increasing number of PS I 3D structures deposited in the Protein Data Bank (PDB). The Triangular Spatial Relationship (TSR)-based algorithm converts 3D structures into integers (TSR keys).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!