[Investigation of cerebral blood volume measurement].

Purpose: Cerebral blood blow (ml/100g/min) (CBF) and cerebral blood volume (%) (CBV) were determined in 102 patients (68 men and 34 women; average age, 55.6 years) with diagnostic cerebral blood flow accident.

Methods: CBF was obtained by xenon inhalation computed tomography (Xe CT) and transit time (TT) by perfusion CT. CBV was calculated under the expression CBV=CBF x TT. The patients were divided into three categories: mild (outpatient), moderate (inpatient), and serious (dead), and CBF and CBV were compared between categories.

Results: On regions of interest (ROI) in the thalamus, the value for mild cases was 58.8+/-10.4 ml/100g/min (CBF) and that for moderate cases was 40.2+/-19.4, a significant difference. In serious cases, CBV was decreased in the thalamus, but there was no difference in CBF between mild and moderate cases.

Conclusion: CBV was useful for determining prognosis in severe cases of diagnostic cerebral blood flow accident.