This paper presents computer simulations of pressure driven viscous flows that creep in two dimensions (Hele-Shaw cells). We model the time and spatial evolution of free liquid-gas interfaces perturbed by solid obstacles of various configurations such as wedges, steps, and ellipses. Our goal is to study short- and long-scale obstacle effects on the interface shape and velocity. Specific focus is given to the dynamics of a triple (gas-liquid-solid) contact line, which determines local wetting of obstacles. As a principal contribution, we derive a functional relationship between the contact line velocity and the obstacle geometry.
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http://dx.doi.org/10.1103/PhysRevE.69.016310 | DOI Listing |
Cytotherapy
January 2025
Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. Electronic address:
Background/aims: Human mesenchymal stromal cells (hMSC) are multipotent adult cells commonly used in regenerative medicine as advanced therapy medicinal products. The expansion of these cells in xeno-free supplements is highly encouraged by regulatory agencies due to safety concerns. However, the number of supplements with robust performance and consistency for hMSC expansion are limited.
View Article and Find Full Text PDFJ Colloid Interface Sci
April 2025
State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address:
Conventional light-driven antimicrobial strategies of zinc oxide (ZnO) are limited by inadequate illumination in dark environments. In this study, carboxylated cellulose nanocrystals (MCNC) mediated flower-like ZnO (C@Z) with self-promoted reactive oxygen species release under dark is fabricated. The adsorption of Zn ions on MCNC prompts the growth of ZnO along the (002) crystal plane, forming a flower-like hybrid with superior dispersibility and oxygen vacancies compared to MCNC-free ZnO, which exposes the (100) plane.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Institute of Basic and Translational Medicine & Shaanxi Key Laboratory of Brain Disorders, Xi'an Medical University, Xi'an, 710021, Shaanxi Province, PR China; Engineering Research Center of Brain Diseases Drug Development, Universities of Shaanxi Province, Xi'an Medical University, Xi'an, 710021, Shaanxi Province, PR China. Electronic address:
Background: Accurate quantification of microRNA (miRNA) is of great significance because it provides opportunities for the accurate early diagnosis of a series of human diseases including cancers. Currently, complicated nucleic acid amplification technologies are always required for the highly sensitive miRNA detection. The introduction of nucleic acid signal amplification coupled with various enzymes will inevitably lead to tedious work and increase the complexity of the analysis process.
View Article and Find Full Text PDFOcul Surf
January 2025
Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea, 37673; Department of Mechanical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea, 37673. Electronic address:
Purpose: To introduce and validate quantitative oblique back-illumination microscopy (qOBM) as a label-free, high-contrast imaging technique for visualizing conjunctival goblet cells (GCs) and assessing their functional changes.
Methods: qOBM was developed in conjunction with moxifloxacin-based fluorescence microscopy (MBFM), which was used for validating GC imaging. Initial validation was conducted with polystyrene beads, followed by testing on normal mouse conjunctiva under both ex-vivo and in-vivo conditions.
J Environ Manage
January 2025
Changzhou Key Laboratory of Biomass Green, Safe and High Value Utilization Technology, Institute of Urban and Rural Mining, Changzhou University, No.21 Gehu Road, Wujin District, Changzhou, 213164, China; National-Local Joint Engineering Research Center for Biomass Refining and High-Quality Utilization, Changzhou University, No.21 Gehu Road, Wujin District, Changzhou, 213164, China. Electronic address:
Erythromycin is becoming one of the most common contaminants detected in surface water and wastewater, which poses a potential risk to ecological systems and human health. Until now, there is still no effective way to eliminate it. Herein, a novel and efficient erythromycin-degrading fungus Peniophora incarnata F1, capable of utilizing erythromycin as its sole source of carbon and energy, was isolated from contaminated sludge.
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