The NHS Breast Screening Programme is changing working practices in response to increased workload and manpower shortages. Radiographers are being trained as film readers. Computer aids are being considered. We have evaluated the impact of prompts placed by the R2 ImageChecker 1000 on the sensitivity and specificity of film readers, including non-radiologist film readers. 30 radiologists, 5 breast clinicians and 15 radiographers each read 180 films, including 60 cancers (20 false negative interval cases and 40 screen detected cancers). Each reader read each case twice, once with and once without computer prompts. The order in which the reading sessions were carried out was randomized separately for each reader. 36 out of 40 screen-detected cases were prompted by the ImageChecker, a sensitivity of 90%. Eight out of 20 interval cases were prompted, a sensitivity of 40%. No significant difference was found for readers' sensitivity or specificity between the prompted and unprompted conditions. No significant difference was found between the sensitivity and specificity of the different groups of film reader. No difference in impact of prompts was found for well or poorly performing film readers. The result suggests that this version of the ImageChecker would not have a significant impact on the UK screening programme.
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http://dx.doi.org/10.1259/bjr/34203805 | DOI Listing |
Polymers (Basel)
December 2024
Medical College, Inner Mongolia Minzu University, Tongliao 028043, China.
The present study aimed to explore an ideal delivery system for triptolide (TPL) by utilizing the thin-film hydration method to prepare drug-loaded, folate-modified mixed pluronic micelles (FA-F-127/F-68-TPL). Scanning electron microscopy and atomic force microscopy showed that the drug-loaded micelles had a spherical shape with a small particle size, with an average of 30.7 nm.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
November 2024
Clinical Research Center, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Purpose: Breast density assessment is an essential component of risk-stratified and supplemental breast cancer screenings for the future generation. International collaborative research and cooperation are required to determine global trends and differences in mammographic breast density. Due to the cost and energy associated with the use of film or digital mammograms, international breast density assessment studies tend to be challenging.
View Article and Find Full Text PDFBMC Microbiol
September 2024
Department of Life Sciences and Health, Faculty of Health Sciences, Oslo Metropolitan University, Postbox 4, St. Olavs Plass, Oslo, 0130, Norway.
Emerg Radiol
September 2024
Radiology Department, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL, 32224, USA.
Purpose: For acute stroke patients requiring MR examination and unable to provide a reliable history, screening for potentially MRI-incompatible objects (PMIOs) typically necessitates the use of plain-film radiographs (PFRs). However, using a whole body CT scout at the time of non-contrast head CT scans can preclude critical delays. Here, we aim to compare the effectiveness of PFRs and CT scouts in detecting PMIOs.
View Article and Find Full Text PDFBackground: Artificial intelligence (AI) based computer-aided detection devices are recommended for screening and triaging of pulmonary tuberculosis (TB) using digital chest x-ray (CXR) images (soft copies). Most AI algorithms are trained using input data from digital CXR Digital Imaging and Communications in Medicine (DICOM) files. There can be scenarios when only digital CXR films (hard copies) are available for interpretation.
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