Examination of the aerial portions of Cleome spinosa yielded five new cembranes, named cleospinols A (1), B (3), C (4), and D (5), and the 3'-hydroxy-iso-pentan-10-oate ester of cleospinol A (2). The cleospinols were determined to be derivatives of 10,13-dihydroxy-4,12-dimethyl-1-(1-methylethenyl)-11(E)-cyclotetradecene on the basis of spectroscopic data interpretation.
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