The World Health Organization (WHO) has used econometric methods to measure the efficiency of health care systems. We assess the robustness of WHO results to definitions of efficiency and statistical procedures. Originally analysed by the WHO, the data are for 1997 (50 countries) and 1993-1997 (141 countries). The efficiency of each country in promoting population health is estimated after taking into account health care expenditure, all other expenditure and education levels. Efficiency scores are compared under different definitions of efficiency and different estimation methods. The results show that the country rankings and efficiency scores are sensitive to the definition of efficiency and choice of model specification. We conclude that econometric methods can yield insights into complex socioeconomic phenomena. However, the lack of robust results to reasonable alternative specifications suggests that it is premature to use the methods adopted by the WHO to construct league tables of health systems.
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Infect Control Hosp Epidemiol
March 2025
Department of Pharmaceutical Care, University of Iowa Health Care, Iowa City, IA, USA.
Background: Concerns about penicillin-cephalosporin cross-reactivity have historically led to conservative prescribing and avoidance of cephalosporins in patients with penicillin allergy labels, potentially causing suboptimal outcomes. Recent evidence suggests a lower risk of cross-reactivity, prompting a reassessment of alert systems.
Objective: To assess the impact of limited penicillin cross-reactivity alerts on outpatient cephalosporin use and the incidence of adverse reactions in a healthcare setting.
OMICS
March 2025
Centre for Integrative Omics Data Science (CIODS), Yenepoya (Deemed to be University), Mangalore, India.
Intracellular calcium signaling is a cornerstone in cell biology and a key molecular target for human health and disease. Calcium/calmodulin dependent protein kinase kinases, CAMKK1 and CAMKK2 are serine/threonine kinases that contribute to the regulation of intracellular calcium signals in response to diverse stimuli. CAMKK1 generally has stable dynamics, whereas CAMKK2 dysregulation triggers oncogenicity and neurological disorders.
View Article and Find Full Text PDFMol Nutr Food Res
March 2025
ProBacLab, Laboratório de Microbiologia de Alimentos, Departamento de Alimentos e Nutrição Experimental, Food Research Center, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, SP, Brazil.
The UN Sustainable Development Goal 2 (Zero Hunger) highlights the need to produce sufficient food commodities to meet the world's population demands and combat hunger, while also respecting the environment and adhering to sustainability principles. Since the beginning of the 21st century, new ideas, ingredients, and technologies have emerged that could significantly transform the food industry. These transformations may alter the rules of food production by integrating traditional knowledge with new technologies and scientific advancements.
View Article and Find Full Text PDFGlob Health Action
December 2025
Department of Epidemiology and Global Health, Medical Faculty, Umeå University, Umeå, Sweden.
The balls are rolling for climate change, with increasing vulnerability to women and children related to climate extreme events. Recent evidence has shown that acute exposure to heat wave during pregnancy can be associated with adverse health outcomes in childhood, with the risk being significantly higher among socially disadvantaged population, despite their lack of contribution to global carbon dioxide emissions and the rising global ambient temperature. This unequal impact requires utmost attention to develop tools, establish interdisciplinary teams, and to implement evidence-based interventions for the betterment of women and children in climate-vulnerable populations.
View Article and Find Full Text PDFBiosaf Health
December 2024
Vanke School of Public Health, Tsinghua University, Beijing 100084, China.
In the last century, global pandemics have been primarily driven by respiratory infections, which consistently rank among the top 20 causes of death worldwide. The coronavirus disease 2019 (COVID-19) pandemic has underscored the intricate nature of managing multiple health crises simultaneously. In recent years, climate change has emerged as a major biosafety and population health challenge.
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