Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
This study reports the results obtained 36 months after treating deep periodontal defects with amelogenins. Results at 12 months have already been published. Sixteen of 21 patients completed the 3-year recall program. This study confirms after 3 years the results obtained at 1 year: Probing pocket depth decreased from 7.87 +/- 2.03 mm to 2.93 +/- 2.19 mm; recession increased from 2.20 +/- 1.42 mm to 2.93 +/- 1.87 mm; and attachment level decreased from 10.07 +/- 2.28 to 5.87 +/- 2.59 mm. No statistically significant difference was found between the data collected at 12 and 36 months. The standardized radiographs, digitized and analyzed with purpose-developed software, did not show any appreciable increase in bone volume, but only improved mineralization of the preexisting bone after 3 years using Emdogain without grafts.
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