Electronic data capture helps improving the quality of clinical research; mainly yielding a more reliable data collection process, but also introducing new resources for controlling the execution of clinical trials and facilitating the monitoring tasks. The protocol can be implemented rather than followed, and tools are at hand to help minimising the human error. The principal difficulty in the use of the electronic data capture lays in a more complex set up. This forces the adaptation of the people involved in the execution of clinical trials to a different workflow. In the future, most of the clinical research will use electronic data capture systems, and the paper shall be left for a few particular cases.
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http://dx.doi.org/10.1157/13057540 | DOI Listing |
J Chem Inf Model
January 2025
School of Information Science & Engineering, Lanzhou University, Lanzhou 730000, China.
Efficient and accurate drug-target affinity (DTA) prediction can significantly accelerate the drug development process. Recently, deep learning models have been widely applied to DTA prediction and have achieved notable success. However, existing methods often encounter several common issues: first, the data representations lack sufficient information; second, the extracted features are not comprehensive; and third, most methods lack interpretability when modeling drug-target binding.
View Article and Find Full Text PDFGigascience
January 2025
Leibniz Institute for the Analysis of Biodiversity Change, Museum Koenig Bonn, 53113 Bonn, Germany.
Background: In this study, we present an in-depth analysis of the Eurasian minnow (Phoxinus phoxinus) genome, highlighting its genetic diversity, structural variations, and evolutionary adaptations. We generated an annotated haplotype-phased, chromosome-level genome assembly (2n = 50) by integrating high-fidelity (HiFi) long reads and chromosome conformation capture data (Hi-C).
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J Phys Chem Lett
January 2025
Department of Process Engineering and Technology of Polymer and Carbon Materials, Wroclaw University of Science and Technology, Wyb. St. Wyspiańskiego 27, 50-370 Wrocław, Poland.
We investigate a continuous electrochemical pH-swing method to capture CO from a gas phase. The electrochemical cell consists of a single cation-exchange membrane (CEM) and a recirculation of a mixture of salt and phenazine-based redox-active molecules. In the absorption compartment, this solution is saturated by CO from a mixed gas phase at high pH.
View Article and Find Full Text PDFHealth Sci Rep
January 2025
School of Health Sciences, Faculty of Medicine and Health, Örebro University Örebro Sweden.
Background And Aim: Tonsil-surgery is a common treatment for tonsillitis and upper-airway obstruction. Health benefits are a key point of clinical concern. Aim: To evaluate health benefits 6-months after pediatric tonsil-surgery and to examine the influence of the perioperative period on health-related quality of life (HRQoL).
View Article and Find Full Text PDFData Brief
February 2025
Department of Computer Science, FEL, Czech Technical University in Prague, Technická 2, Prague 126 627, Czech Republic.
This data article introduces a new network dataset created to help understand how geographical location impacts the quality, type, and amount of incoming network attacks received by honeypots. The dataset consists of 12.4 million network flows collected from nine low-interaction honeypots in nine cities across the world for 65 days, from April 29th to July 1st, 2024.
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