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Identification of srv, a PrfA-like regulator of group A streptococcus that influences virulence. | LitMetric
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Identification of srv, a PrfA-like regulator of group A streptococcus that influences virulence.

Sean D Reid Alison G Montgomery James M Musser

Infect Immun

Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA.

Published: March 2004

We have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of virulence in Listeria monocytogenes.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC355993PMC
http://dx.doi.org/10.1128/IAI.72.3.1799-1803.2004DOI Listing

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