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E74-like ETS transcription factor 3 expression and regulation in human intervertebral disc.
JOR Spine
March 2025
SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), The NEIRID Group (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases) Santiago University Clinical Hospital Santiago de Compostela Spain.
Background: Intervertebral disc degeneration (IVDD) is one of the main causes of chronic low back pain. The degenerative process is often initiated by an imbalance between catabolic and anabolic pathways. Despite the large socio-economic impact, the initiation and progress of disc degeneration are poorly understood.
View Article and Find Full Text PDFMycobacteriophages are viruses that specifically infect bacteria of the Mycobacterium genus. A substantial collection of mycobacteriophages has been isolated and characterized, offering valuable insights into their diversity and evolution. This collection also holds significant potential for therapeutic applications, particularly as an alternative to antibiotics in combating drug-resistant bacterial strains.
View Article and Find Full Text PDFMiMICRI: Towards Domain-centered Counterfactual Explanations of Cardiovascular Image Classification Models.
FACCT 24 (2024)
June 2024
IBM Research Cambridge, Massachusetts, USA.
The recent prevalence of publicly accessible, large medical imaging datasets has led to a proliferation of artificial intelligence (AI) models for cardiovascular image classification and analysis. At the same time, the potentially significant impacts of these models have motivated the development of a range of explainable AI (XAI) methods that aim to explain model predictions given certain image inputs. However, many of these methods are not developed or evaluated with domain experts, and explanations are not contextualized in terms of medical expertise or domain knowledge.
View Article and Find Full Text PDFFetal Cardiac Function and Remodeling in In Vitro Fertilization Pregnancies: A Tertiary Center Experience.
Echocardiography
February 2025
Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, Ankara, Turkey.
Purpose: To investigate fetal cardiac functions and remodeling in pregnancies conceived via in vitro fertilization (IVF).
Methods: This prospective case-control study included 40 singleton IVF pregnancies and 46 uncomplicated control pregnancies at 28-36 weeks of gestation. The IVF group consisted of pregnancies applied to the outpatient clinic, excluding those with anatomical or chromosomal abnormalities.
Friction of Laser-Textured Zirconia Coated with a Platelet-Rich Fibrin.
J Dent Res
January 2025
Center for MicroElectroMechanical Systems, Universidade do Minho, Guimarães, Portugal.
In the present in vitro study, we evaluated the adhesion of an injectable platelet-rich fibrin (i-PRF) to laser-textured zirconia surfaces and their resultant friction behavior against bone tissue. Three types of zirconia surfaces were compared regarding the i-PRF coating effects: 1) grit blasted with 250-μm spherical alumina particles and acid etched with 20% hydrofluoric acid (ZLA), 2) laser textured with a random (RD) surface pattern, or 3) laser textured with a designed pattern based on 16 lines and 8 passages (L16N8). The coefficient of friction (COF) of the specimens was assessed on a reciprocating sliding pin-on-plate tribometer at 1-N normal load, 1 Hz, and a 2-mm stroke length.
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