Background: Using univariate and multivariate variance components linkage analysis methods, we studied possible genotype x age interaction in cardiovascular phenotypes related to the aging process from the Framingham Heart Study.
Results: We found evidence for genotype x age interaction for fasting glucose and systolic blood pressure.
Conclusions: There is polygenic genotype x age interaction for fasting glucose and systolic blood pressure and quantitative trait locus x age interaction for a linkage signal for systolic blood pressure phenotypes located on chromosome 17 at 67 cM.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866541 | PMC |
| http://dx.doi.org/10.1186/1471-2156-4-S1-S34 | DOI Listing |
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