A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of the leaves was also found to exhibit antimicrobial and cytotoxic activities.
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http://dx.doi.org/10.1080/1057563031000122121 | DOI Listing |
Nat Prod Res
July 2024
Western Guangdong Characteristic Biology and Medicine Engineering and Research Center, School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang, P.R. China.
Two new sulphur-containing amides, glylucidamides C-D (-), along with twelve known analogues (-) were isolated and characterised from the leaves of . The chemical structures of and were elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons their data with those reported in the literatures. All new compounds were evaluated for their anti-inflammatory activities examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.
View Article and Find Full Text PDFFitoterapia
March 2023
Western Guangdong Characteristic Biology and Medicine Engineering and Research Center, School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524000, China; Guangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China. Electronic address:
Fourteen new sulphur-containing amides, glycocramides A-N (1-14), as well as nine known analogues (15-23) were isolated and characterized from Glycosmis craibii Tanaka. The chemical structures of new sulphur-containing amides 1-14 were ambiguously elucidated by extensive spectroscopic methods, while the known compounds 15-23 were identified by the comparison of their experimental spectral data with those described data in the literatures. The antiproliferative effects of all isolated sulphur-containing amides were evaluated in vitro.
View Article and Find Full Text PDFPhytochemistry
October 2021
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), An Institute of National Importance, Government of India, Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Opp. Air Force Station, Palaj, Gandhinagar, 382355, Gujarat, India. Electronic address:
The present article is a systematic and constructive review of the traditional medicinal uses, chemistry, pharmacology, toxicology, and formulation aspects of Glycosmis species. The genus Glycosmis comprise 51 accepted species broadly distributed in Australia, China, India, and South-East Asia. Traditionally, Glycosmis species are used in folk medicines to treat cancer, anaemia, rheumatism, fever, cough, liver-related problems, skin ailments, intestinal worm infections, wounds, and facial inflammation.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
October 2021
Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Acrylamide (ACR) has been previously associated with male sexual dysfunction and infertility. Eruca sativa (L.) (arugula or rocket) have been widely used in traditional remedies in Mediterranean region and western Asia and was known for its strong aphrodisiac effect since Roman times.
View Article and Find Full Text PDFLuminescence
August 2021
Food and Nutraceutical Division, CSIR - Institute of Himalayan Bioresource Technology, Palampur, India.
Metals play an important role in various metabolic activities in the human body, but above desired concentrations, a role reversal occurs that causes deadly outcomes viz., cancer. Metals cannot be cracked down and are non-biodegradable.
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