The aim of this study is to identify the major mechanisms and the aetiology of ocular trauma in children population. It is a retrospective study of 138 children treated for ocular injuries in Clinica I Ophthalmology, between 1 January 1997 and 31 December 1999. The mean age of study was 9.9 years for girls and for boys 10.7 years. Boys were more frequently involved as girls (ratio 3.6/1). Injuries were in 25% to have occurred at home and in 46% with their own toys. In conclusions, ocular trauma occurs most frequently in the home setting, after sharp tools. It is necessary to treat trauma early and complete for prevention amblyopia.
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Int Ophthalmol
January 2025
Department of Ophthalmology, Rutgers New Jersey Medical School, Institute of Ophthalmology and Visual Science, Newark, NJ, USA.
Purpose: The purpose of this study is to analyze the trends and characteristics of ocular trauma research published from 2000 to 2022 to delineate the trajectory of the field's research, provide information about the network of key contributors, and help determine future research strategies and direction.
Methods: Web of Science was queried for published works using a series of keywords relating to ocular trauma: "globe rupture", "ruptured globe", "globe injury", "ocular trauma", "intraocular foreign body", "eye trauma", "eye injury", and "traumatic endophthalmitis". All article information was compiled using the VOSviewer software.
Int Ophthalmol
January 2025
Department of Ophthalmology, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Türkiye.
Purpose: The aim of the present study is to examine the demographic data and clinical features of ocular surface injuries due to thermal burns and to evaluate LSCD in the light of global consensus.
Methods: Thirty-three eyes of 20 cases with ocular surface injury due to thermal burn who attended to the clinic between 2012 and 2023 were included in the study. LSCD severity was staged according to the global consensus which was published in 2019.
Sci Rep
January 2025
Department of Chemistry and Biochemistry, The University of Notre Dame, 305 McCourtney Hall, Notre Dame, IN, 46556, USA.
The heat shock protein 90 (Hsp90) family of molecular chaperones mediates the folding and activation of ~ 400 client proteins, many of which contribute to oncogenesis. As a result, Hsp90 pan-inhibitors, which inhibit all four Hsp90 isoforms, have been investigated in the clinic for the treatment of cancer. Unfortunately, detrimental side effects were observed and hindered the clinical development of pan-Hsp90 inhibitors.
View Article and Find Full Text PDFTorture
January 2025
MD. Private practice, Zurich, Switzerland. Correspondence to
Dear Editor-in-chief: Thank you for focussing on this troubling subject in your issue 1/2024. It confirms that many of the difficulties involved are similar worldwide. Countries that use less-lethal weapons include Switzerland, the only Western European democracy besides France to employ multiple kinetic impact projectiles.
View Article and Find Full Text PDFCont Lens Anterior Eye
January 2025
Department of Regeneration and Cell Therapy, Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER), Avda. Américo Vespucio 24, 41092 Seville, Spain.
Purpose: To evaluate the role of contact lenses (CLs) in visual rehabilitation following keratoplasty.
Methods: Four databases, including PubMed, Scopus, Web of Science, and Embase were systematically searched for studies published between January 2010 and July 2023. Visual outcomes, daily wearing duration, subjective comfort, rate and etiology of CL discontinuation, corneal endothelial cell density, central corneal thickness, and complications were extracted.
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