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Association Between Clinical Measures of Depth of Sedation and Multimodal Cerebral Physiology in Acute Traumatic Neural Injury.
Neurotrauma Rep
October 2024
Biomedical Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, Canada.
Neurointensive care primarily focuses on secondary injury reduction, utilizing a variety of guideline-based approaches (including administration of high-dose sedation) to reduce the injured state. However, titration of sedation is currently based on the Richmond Agitation Sedation Scale (RASS), a subjective clinical grading score of a patient's response to external physical stimuli, and not an objective measure. Therefore, it is likely that there exists substantial variation in objective sedation depth for a given clinical grade in these patients, leading to undesired sedation depths and cerebral physiological consequences.
View Article and Find Full Text PDFBispectral index monitoring: Optimizing anesthesia in rigid bronchoscopy.
Tuberk Toraks
September 2024
Clinic of Anesthesiology and Reanimation, Başakşehir Çam and Sakura City Hospital, İstanbul, Türkiye.
Article Synopsis
- This study explores how using the bispectral index (BIS) monitoring during rigid bronchoscopy can improve anesthesia management and patient outcomes, an area that lacks substantial research.!
- A total of 155 adult patients were analyzed, split into two groups: one that utilized BIS monitoring and another that employed traditional anesthesia methods, with no notable demographic differences between the groups.!
- The results showed that the BIS group required significantly less propofol and prednol compared to the conventional group, indicating more efficient anesthetic delivery, while remifentanil usage approached a level of statistical significance for reduction as well.!
Comparison of bispectral index-guided endoscopic ultrasonography with continuous vs. intermittent infusion of propofol: a retrospective study in Japan.
Clin Endosc
November 2024
Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka, Japan.
Background/aims: This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS).
Methods: A total of 427 consecutive patients who underwent EUS between May 2018 and February 2019 were enrolled in this study. The patients were divided into two propofol infusion groups: continuous (n=207) and intermittent (n=220).
Intraoperative microelectrode recording during asleep deep brain stimulation of subthalamic nucleus for Parkinson Disease. A case series with systematic review of the literature.
Neurosurg Rev
July 2024
Department of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli 8, Rome, 00168, Italy.
The use of microelectrode recording (MER) during deep brain stimulation (DBS) for Parkinson Disease is controversial. Furthermore, in asleep DBS anesthesia can impair the ability to record single-cell electric activity.The purpose of this study was to describe our surgical and anesthesiologic protocol for MER assessment during asleep subthalamic nucleus (STN) DBS and to put our findings in the context of a systematic review of the literature.
View Article and Find Full Text PDFComparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting Surgery: A Prospective Randomized Single-Blinded Study.
J Cardiothorac Vasc Anesth
September 2024
Cardiothoracic and Vascular Anaesthesiology Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India.
Objectives: To compare the incidence of delirium and early (at 1 week) postoperative cognitive dysfunction (POCD) between propofol-based total intravenous anesthesia (TIVA) and volatile anesthesia with sevoflurane in adult patients undergoing elective coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass (CPB).
Design: This was a prospective randomized single-blinded study.
Setting: The study was conducted at a single institution, the Sree Chitra Tirunal Institute for Medical Sciences and Technology, a tertiary care institution and university-level teaching hospital.
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