AI Article Synopsis
- A 24-year-old man with recurrent peptic ulcers and elevated gastrin levels was diagnosed with a duodenal web after a thorough investigation for gastrinoma.
- Surgical treatment involved removing the affected section of the duodenum and performing a gastroduodenostomy with selective vagotomy, leading to normalized gastrin levels within six weeks post-surgery.
- This case highlights the importance of considering congenital anomalies as potential causes of gastric outlet obstruction in adults experiencing recurring peptic ulcers and hypergastrinemia.
Article Abstract
We present the case of a 24-year-old man with recurrent peptic ulcers and hypergastrinemia, in whom a multidisciplinary investigation for gastrinoma revealed a duodenal web. The affected duodenal segment was excised, and a gastroduodenostomy with highly selective vagotomy was performed. Postoperative serum gastrin levels returned to the normal range over the next 6 weeks. Congenital duodenal anomalies are unusual causes of gastric outlet obstruction in adults. Chronic gastric outlet obstruction secondary to an adult duodenal web can induce neurohumoral changes in gastric function, which enhance both acid output and gastrin secretion. This case reminds clinicians to consider congenital anomalies in adults presenting with recurrent peptic ulcers and hypergastrinemia.
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| http://dx.doi.org/10.1016/S0149-7944(03)00080-1 | DOI Listing |
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