AI Article Synopsis
- The study aimed to examine the carotid artery's intima-media thickness (IMT) and plaque score in patients with acute coronary syndrome (ACS) and how they relate to high-sensitivity C-reactive protein (hs-CRP) levels.
- In the research, 30 ACS patients, 29 with stable angina pectoris (SAP), and 17 control subjects underwent high-resolution ultrasound to measure IMT and plaque scores along with hs-CRP levels.
- Results indicated that both IMT and plaque scores (soft and hard) were significantly higher in the ACS group compared to the SAP and control groups, with hs-CRP levels also rising considerably in the ACS group, showing a positive correlation with the IMT and
Article Abstract
Objective: To study the intima-media thickness (IMT), plaque score in the carotid artery of patients with acute coronary syndrome (ACS) and the relationship between high-sensitivity C-reactive protein (hs-CRP) and the plaque score.
Methods: Using high-resolution ultrasonic instrument, IMT and the plaque score in the carotid artery were detected in 30 patients with ACS, 29 patients with stable angina pectoris SAP and 17 control subjects, in addition to the measurement of hs-CRP.
Results: Compared with SAP and control groups, IMT, total plaque score, soft and hard plaque scores in the carotid artery in ACS group were significantly increased (P<0.001). Hs-CRP (4.336+/-1.334 mg/L) in ACS group were significantly increased (P<0.001) as compared with that in SAP group (2.205+/-0.458 mg/L) and control group (1.625+/-0.434 mg/L). Hs-CRP had positive relationship with the IMT, whole plaque score, soft and hard plaque scores in the carotid artery, respectively.
Conclusion: IMT, total plaque score, soft and hard plaque scores in the carotid artery in ACS group are significantly increased, and hs-CRP is positively related to IMT, total plaque score, soft and hard plaque scores in the carotid artery, respectively.
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