Co-agglutination (Co-A): a rapid test for the diagnosis of experimental trichinellosis.

J Egypt Soc Parasitol

Department of Parasitology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Published: August 2003

AI Article Synopsis

  • Co-agglutination test (Co-A test) shows potential as a diagnostic tool for detecting T. spiralis antigens in mice, compared to the established ELISA method.
  • Both tests effectively identified the antigens in the urine of infected mice around 30 days post-infection.
  • Co-A test is highlighted as an accurate, easy, and quick method suitable for large-scale testing for trichinellosis.

Article Abstract

Co-agglutination test (Co-A test) which has a wide application spectrum in bacterial diseases has been used for the detection of some parasitic infections. This work was to evaluate Co-A test as a new diagnostic tool in detection of T. spiralis antigens in both sera and urine of experimentally infected mice as compared with ELISA, for the diagnosis of trichinellosis. The results obtained by Co-A test were closely correlated with those of ELISA. The most important was that both tests were capable to detect T. spiralis antigen in urine of light and heavily infected mice only at the 30th days post infection. So, Co-A is an accurate, easy and rapid test that can be used on large scales for diagnosis of trichinellosis.

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