Aim: To compare clinical, cost-effect efficacies and safety of simvastatin Zokor and generic Vasilip in correction of dislipoproteinemia in patients with ischemic heart disease.
Material And Methods: The original statin Zokor and generic statin Vasilip were given for 8 weeks in a dose 20 mg/day.
Results: Vasilip and Zokor demonstrated similar hypolipidemic efficacy and safety, but Vasilip administration was more cost-effective.
Conclusion: Simvastatin Vasilip is recommended for wider use in clinical practice because it is clinically and cost effective.
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N Engl J Med
September 2024
From the State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology (X.-A.Z., Y.-D.M., Y.-F.Z., Z.-Y.H., J.-T.Z., S.H., G.W., S.L., X.W., L.Z., G.-Q.S., C.P., R.W., H.-H.G., B.-G.J., H.L., W.L.), and the Institute of Medical Prevention and Control of Public Health Emergencies, Characteristic Medical Center of the Chinese People's Armed Police Force (F.T.), Beijing, Changchun Institute of Veterinary Medicine, Chinese Academy of Agricultural Sciences, Changchun (Y.-D.M., N.L., C.L.), the School of Public Health, Anhui Medical University, Hefei (Z.-Y.H., X.W., H.L., W.L.), Medical Detachment of Inner Mongolia Autonomous Region Forest Fire Brigade Daxing'anling Branch, Yakeshi (W.-J.L.), the First Affiliated Hospital of Jinzhou Medical University, Jinzhou (H.-X.Y.), Dandong Infectious Disease Hospital, Dandong (J.-Q.Z.), and the Center for Disease Control and Prevention in Zhalainuoer District, Hulunbuir (L.-F.J.) - all in China.
Animals (Basel)
August 2024
College of Grassland Resources and Environment, Inner Mongolia Agricultural University, Hohhot 010011, China.
Animals (Basel)
August 2023
School of Geography and Planning, Sun Yat-sen University, Guangzhou 510275, China.
The soil temperature is a key factor affecting the fragile terrestrial ecosystems on the Qinghai-Tibet Plateau, and has been remarkably altered by the soil mammal's disturbance. This study first analyzed the soil temperature variation in grassland, mound, and bald patch under the disturbance of plateau zokor () from October 2018 to July 2020 in the Qinghai Lake watershed. Then, the SHAW (simultaneous heat and water) model was used to simulate the soil temperature change of three land surface types, and the sensitivity of soil temperature to environmental parameters before and after the disturbance was explored.
View Article and Find Full Text PDFBMC Bioinformatics
June 2023
National Center of Mathematics and Interdisciplinary Sciences, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, 100190, China.
Background: Closing gaps in draft genomes leads to more complete and continuous genome assemblies. The ubiquitous genomic repeats are challenges to the existing gap-closing methods, based on either the k-mer representation by the de Bruijn graph or the overlap-layout-consensus paradigm. Besides, chimeric reads will cause erroneous k-mers in the former and false overlaps of reads in the latter.
View Article and Find Full Text PDFAnimals (Basel)
January 2023
College of Grassland Science, Gansu Agricultural University, Key Laboratory of Grassland Ecosystem of the Ministry of Education, Engineering and Technology Research Center for Alpine Rodent Pest Control, National Forestry and Grassland Administration, Lanzhou 730070, China.
There are considerable challenges involved in studying the behavior of subterranean rodents owing to the underground nature of their ecotope. Seismic communication plays a crucial role in the behavior of subterranean rodents, particularly solitary ones. The plateau zokor (Eospalax baileyi), a solitary subterranean rodent species endemic to the Qinghai−Tibet Plateau, will usually occupy empty neighboring tunnels in order to extend their territory.
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