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Medicine (Baltimore)
November 2024
Department of Anatomy, Cukurova University Faculty of Medicine, Adana, Turkey.
Background: Piriformis syndrome, which is seen as the cause of 0.3% to 6% of low back pain, is a painful condition that occurs as a result of compression of the piriformis muscle on the sciatic nerve. Although there are many studies in the literature about piriformis syndrome, no bibliometric analysis has been found.
View Article and Find Full Text PDFCureus
November 2024
Anesthesiology, Showa University School of Medicine, Tokyo, JPN.
Usually, coccydynia cases are caused by herniated discs, with lower back pain and sciatica as initial symptoms. However, whether lumbar disc herniation causes coccydynia without back pain remains unclear. We report a case of lumbar disc herniation diagnosed as the underlying cause of coccydynia by discoblock.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Acupuncture Anaesthesia Clinical Research Institute, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Background: Metabolic disorders are significant risk factors for peripheral neuropathy (PN) diseases. However, current clinical observational studies cannot fully determine the causal relationships between hypothyroidism (HT) and PN diseases.
Methods: We performed univariate Mendelian randomization (MR) analyses using single nucleotide polymorphisms (SNPs) associated with hypothyroidism and two diseases clinically presented as HT (autoimmune thyroid disease and benign neoplasm of the pituitary gland and craniopharyngeal duct) as instrumental variables.
Clin Rheumatol
January 2025
Cell Therapy and Experimental Surgery of Musculoskeletal System LR18SP11 Lab, Medicine Faculty of Sfax, University of Sfax, Majida Boulila Road, 3029, Sfax, Tunisia.
Curr Comput Aided Drug Des
December 2024
Department of Orthopedics, the Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410005, China.
Objective: The Qing'e Pill (QEP) is widely used to alleviate low back pain and sciatica caused by Intervertebral Disc Degeneration (IDD). However, its active components, key targets, and molecular mechanisms are not fully understood. The aim of this study is to elucidate the molecular mechanisms through which the QEP improves IDD using database mining techniques.
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