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Long-Term Follow-Up of Patients with Axial Spondyloarthritis in Real-Life Setting: Results from Greece of the Multi-Country Registry Proof Study.
Mediterr J Rheumatol
December 2024
"Metropolitan" General Hospital, Piraeus, Greece.
Objectives: The aim of the present analysis was to describe the clinical and demographic characteristics of ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA) patients from Greece who were enrolled in the global PROOF study, and their longitudinal follow-up over 5 years to determine the impact of the disease on quality of life and patient-reported outcomes.
Methods: PROOF was an observational study that enrolled recently diagnosed (<1 year) patients fulfilling the Assessment of SpondyloArthritis International Society classification criteria from rheumatology clinical practices from 29 countries across 6 different geographical regions.
Results: Of the 100 Greek patients enrolled, 85 were classified based on local (investigator) evaluation of sacroiliac radiographs [AS: 56 (65.
Incidence of and Factors Associated with Spontaneous Correction of Postoperative Shoulder Imbalance in Adolescent Idiopathic Scoliosis Patients: A Retrospective Cohort Study.
Indian J Orthop
February 2025
Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, 10700 Bangkok Thailand.
Background: As far as we know, no study has investigated spontaneous postoperative shoulder imbalance (PSI) correction in adolescent idiopathic scoliosis (AIS) patients. The objective is to assess the incidence of and associated factors for spontaneous PSI correction in AIS patients.
Methods: The study evaluated 144 postoperative AIS patients with PSI aged 10-20 years between 2010 and 2018.
Evaluating the Corrected Femoroepiphyseal Acetabular Roof Index in Patients With Borderline Dysplasia Undergoing Periacetabular Osteotomy or Hip Arthroscopy.
Orthop J Sports Med
January 2025
Balgrist University Hospital, Orthopaedic Department, University of Zurich, Zurich, Switzerland.
Background: Identifying hip instability in symptomatic patients with borderline dysplasia of the hip (BDH) is of paramount importance, as it can influence both surgical decision-making and surgical outcomes. The femoroepiphyseal acetabular roof (FEAR) index is strongly affected by the hip adduction/abduction angle during the pelvic radiograph, which has not yet been considered in the recommended threshold values.
Purpose: To compare the corrected FEAR index in symptomatic patients with BDH treated with pelvic periacetabular osteotomy (PAO) or hip arthroscopy.
Long-term Outcomes After Anterior Cruciate Ligament Reconstruction With 3 Different Surgical Techniques: A Prospective Randomized Clinical and Radiographic Evaluation at a Minimum of 20 Years' Follow-up.
Orthop J Sports Med
January 2025
Clinica Ortopedica e Traumatologica II, Istituto Ortopedico Rizzoli, Bologna, Italy.
Background: In recent years, lateral extra-articular tenodesis (LET) has been shown to be promising in reducing the graft failure rate at short-term follow-up. However, there is a lack of studies investigating the incidence of complications and lateral osteoarthritis (OA) after this procedure, and only a few studies have reported long-term results after anterior cruciate ligament (ACL) reconstruction.
Purpose/hypothesis: This study aimed to compare the failure rate, clinical outcomes, and OA incidence of 3 different ACL reconstruction techniques: single-bundle quadrupled hamstring tendon (HT), bone-patellar tendon-bone (BPTB), and over-the-top HT plus LET (HT + LET).
Brief Report: Impact of Maintenance Pemetrexed Cessation on Clinical Outcomes of Patients With Metastatic Nonsquamous NSCLC.
JTO Clin Res Rep
November 2024
Vanderbilt University School of Medicine, Nashville, Tennessee.
Introduction: Combination chemoimmunotherapy including pemetrexed and a PD(L)1 inhibitor is a common first-line systemic therapy approach for patients with metastatic nonsquamous NSCLC. Patients often discontinue maintenance pemetrexed due to adverse effects, and little is known about the impact of maintenance pemetrexed cessation on real-world progression-free survival (rwPFS) and overall survival (OS).
Methods: A total of 121 patients with stage IV or recurrent, metastatic nonsquamous NSCLC treated at Vanderbilt University Medical Center (VUMC) were included in this retrospective analysis.
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