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A comparative analysis in monitoring 24-hour urinary copper in wilson disease: sampling on or off treatment?
Orphanet J Rare Dis
January 2025
Internal Medicine IV, Department of Gastroenterology, University Hospital Heidelberg, INF 410, Heidelberg, 69120, Germany.
Background & Aim: Twenty-four-hour urinary copper excretion (24 h-UCE) is the standard diagnostic tool for dose adjustments in maintenance therapy in Wilson disease (WD) patients. Guidelines lack data if both variants of 24 h-UCE measurement (with or without 48 h of treatment interruption) are equally interpretable.
Methods: Eighty-four patients with a confirmed diagnosis of WD treated with chelators (50% of patients with D-Penicillamine and 50% with trientine) and with pairwise 24-h-UCE values on-therapy and off-therapy were included in the analysis.
Approaches for Analyzing the Relationship Between Spirituality and Health Using Measures Contaminated with Indicators of Mental and Social Health.
J Relig Health
January 2025
School of Psychology & Public Health, College of Science, Health & Engineering, La Trobe University, Victoria, 3086, Australia.
There has been concern raised in religion/spirituality (R/S) research about the use of measures of spirituality that are contaminated by indicators of mental and/or social health. Many of these scales are used widely in published studies examining associations with health, and yet many researchers and reviewers are not aware of contamination issues. We have previously cautioned researchers to be careful in their choice of religious/spirituality (R/S) measures (Koenig and Carey in J Relig Health, 63(5):3729-3743.
View Article and Find Full Text PDFTrigger Point Dry Needling to Reduce Pain and Improve Function and Postural Control in People With Ankle Sprain: A Systematic Review and Meta-Analysis.
J Chiropr Med
September 2024
Department of Health, Nutrition and Exercise Sciences, North Dakota State University, Fargo, North Dakota.
Objective: The purpose of this review was to evaluate the effectiveness of dry needling (DN) to improve function, proprioception, and balance and to reduce pain in individuals with chronic ankle instability (CAI).
Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for this review. We searched PubMed, ISI Web of Knowledge, Scopus, Science Direct, Google Scholar, and ProQuest databases from inception until July 2022 using the PICO (population, intervention, comparison, outcome) method.
New moderationism: medical discourses on alcohol and the decline of drunkenness in interwar Britain.
Mod Br Hist
January 2025
Graduate School of Business Administration, Hitotsubashi University, Tokyo, Japan.
This article explores the significant yet underappreciated role of medical experts in consolidating the promotion of moderate drinking as a viable solution to Britain's alcohol problem during the interwar period. The country's experience with alcohol regulation in the First World War showed that widespread drunkenness could be effectively managed through policies that restricted the availability of alcohol and encouraged moderation. This realization weakened the political standing of the temperance movement, as support for alcohol prohibition and abstinence waned, leading to the liberalization of social attitudes towards drinking.
View Article and Find Full Text PDFConcurrent Evaluation of Restless Leg Syndrome, Neuropathic Pain, and Quality of Life in Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis: Single-Center Data.
Cureus
November 2024
Division of Rheumatology, Department of Internal Medicine, Erciyes University Faculty of Medicine, Kayseri, TUR.
Objective This study aims to investigate the frequency of restless leg syndrome (RLS) and neuropathic pain (NeP) and their effects on the quality of life (QoL) of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). Methods The study included 30 patients with AAV and 30 healthy volunteers. Demographic and clinical parameters and laboratory data were recorded.
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