[Opioid inhibition of oxytocin release from the posterior lobe of the hypophysis and its significance for obstetrical anesthesiology].

The review of literature presents modern experimental and clinical data on opioid inhibition of oxytocin release from posterior hypophysis lobe during pregnancy and in childbirth. The impact of various narcotic analgesics on oxytocin secretion, myometrium contractility and the condition of the fetus and newborn has been assessed. The data on oxytocin blood plasma level are of importance in the clinical practice for selecting the most suitable anesthesia technique during physiological and pathological labour, especially when modern narcotic analgesics (morphine, promedol, fentanyl, tramadol, etc.) are used.