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| http://dx.doi.org/10.1136/sti.28.1.20 | DOI Listing |
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Neurosyphilis-Induced Psychosis in Europe: A Systematic Review of Case Reports.
Pathogens
November 2024
Department of Microbiology and Medical Laboratory Immunology, Medical University of Lodz, 92-213 Lodz, Poland.
Article Synopsis
- The tertiary stage of syphilis involves diverse symptoms, particularly affecting the cardiovascular, neurological, and psychiatric systems, highlighting the need for awareness and interdisciplinary collaboration in treatment.
- A systematic review analyzed 11 case reports focused on organic psychoses associated with tertiary syphilis, revealing that most patients experienced delusions (91%) and hallucinations (81%).
- The study also noted inconsistencies in diagnostic processes but found that treatment largely followed established guidelines, demonstrating that neurosyphilis, despite its complexity, can be effectively managed.
Gummatous neurosyphilis in an elderly patient in the Australian outback: a case report.
J Med Case Rep
November 2021
Intensive Care Unit, Level 4, Royal Adelaide Hospital, Port Road, Adelaide, SA, 5000, Australia.
Introduction: Neurosyphilis is an infection caused by the spirochete Treponema pallidum, which causes infiltration and thickening of brain meninges. Despite being an Old World disease, the rates of infection continue to rise. This clinical challenge involves early and accurate diagnosis, as neurosyphilis masquerades with various clinical symptoms and is often missed during initial presentation to the hospital.
View Article and Find Full Text PDFAnalysis of Fourteen New Cases of Meningovascular Syphilis: Renewed Interest in an Old Problem.
Cureus
August 2021
Neurology, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Oujda, MAR.
Neurosyphilis (NS) remains a public health problem. Several recent reports suggest a worldwide increase in the incidence of this condition. Various syndromes can occur in NS, such as syphilitic meningitis, meningovascular syphilis, parenchymatous and gummatous neurosyphilis.
View Article and Find Full Text PDFThe immunological architecture of granulomatous inflammation in central nervous system tuberculosis.
Tuberculosis (Edinb)
December 2020
Department of Pediatric Infectious Diseases and Immunology, Amsterdam Infection & Immunity Institute, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. Electronic address:
Of all tuberculosis (TB) cases, 1% affects the central nervous system (CNS), with a mortality rate of up to 60%. Our aim is to fill the 'key gap' in TBM research by analyzing brain specimens in a unique historical cohort of 84 patients, focusing on granuloma formation. We describe three different types: non-necrotizing, necrotizing gummatous, and necrotizing abscess type granuloma.
View Article and Find Full Text PDFGummatous penile syphilis.
IDCases
July 2019
Division of Urology, Department of Surgery, Centre Hospitalier Universitaire de Sherbrooke, 3001 12e avenue nord, Sherbrooke, QC J1H5N4, Canada.
Syphilitic gumma involving the penis is a rare manifestation of tertiary syphilis. Only seventeen cases have been reported in the literature. It can mimic other diagnoses such as penile carcinoma.
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