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| http://dx.doi.org/10.1097/00000658-195204000-00014 | DOI Listing |
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Clinical features of atypical solid-type congenital pulmonary airway malformation (CPAM) type 1.
Pediatr Neonatol
December 2024
Division of Fetal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine at the National Center for Child Health and Development, Tokyo, Japan.
Introduction: Type 1 congenital pulmonary airway malformation (CPAM) is characterized by large, dilated cysts that rapidly expand due to aeration immediately after birth, often necessitating surgical resection. In atypical cases of CPAM type 1, fetal T2-weighted magnetic resonance imaging (MRI) reveals a low-intensity solid lung mass containing multiple irregular T2 high-intensity areas.
Methods: Data were retrospectively collected for infants with atypical CPAM type 1 born at our hospital between March 2002 and December 2022.
Study of Imaging Biomarkers as a Prognostic Factor and Guide in the Management of Diabetic Macular Oedema.
Cureus
November 2024
Ophthalmology, Gandhi Medical College and Hamidia Hospital, Bhopal, IND.
Diabetic macular oedema (DME) is a major cause of vision impairment in individuals with diabetes mellitus, characterised by fluid accumulation in the macula due to increased vascular permeability. The growing prevalence of diabetes worldwide has led to an increasing burden of DME on healthcare systems. While current treatment options such as anti-vascular endothelial growth factor (anti-VEGF) injections, corticosteroids, and laser therapy exist, the variability in patient responses highlights the need for reliable prognostic tools.
View Article and Find Full Text PDFHuman colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis.
J Pathol
January 2025
Institut de Recherche en Santé Digestive (IRSD), Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France.
Patients with familial adenomatous polyposis (FAP) harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. There is no validated treatment, and animal models are not sufficient to study FAP. Our aim was to investigate the early events associated with FAP using the intestinal organoid model in a single-center study using biopsies from nonadenomatous and adenomatous colonic mucosa of FAP patients and from healthy controls (HCs).
View Article and Find Full Text PDFImmunohistochemical Investigation of the Proliferative Activity of Odontogenic Cysts and Tumors.
Appl Immunohistochem Mol Morphol
November 2024
Department of Basic Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, 84428, Riyadh 11671, Saudi Arabia.
Odontogenic cysts and tumors exhibit a broad spectrum of biological characteristics. Despite recent advances in understanding the complex nature of these lesions, relatively less is known about the molecular markers involved in key pathogenic steps, such as proliferation and differentiation. This study aimed to elucidate the expression patterns of p63 and Ki-67 in odontogenic lesions, which may influence the management strategies.
View Article and Find Full Text PDFClinical and pathologic characteristics of inflamed juvenile conjunctival nevus and its treatment with immunosuppressant eye drops.
Jpn J Ophthalmol
November 2024
Department of Ophthalmology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, 573-1191, Osaka, Japan.
Purpose: To clarify the clinical and pathologic findings of 7 patients with inflamed juvenile conjunctival nevus (IJCN) treated with tacrolimus.
Study Design: Retrospective study.
Subjects And Methods: The medical records of 7 male patients diagnosed with IJCN between February 2007 and October 2022 at the Kansai Medical University Hospital and Ideta Eye Hospital were retrospectively reviewed.
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